John R Lukens
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Explore the profile of John R Lukens including associated specialties, affiliations and a list of published articles.
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Articles
78
Citations
3421
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Recent Articles
1.
Beiter R, Raghavan T, Suchocki O, Ennerfelt H, Rivet-Noor C, Merchak A, et al.
Heliyon
. 2025 Jan;
11(1):e41635.
PMID: 39866464
Background: Variants in the gene have been identified as a risk factor for late-onset Alzheimer's disease and are linked to decreased white matter integrity in healthy adults. However, the specific...
2.
Samuels J, Lukens J
Cell Mol Immunol
. 2025 Jan;
22(2):208-210.
PMID: 39809887
No abstract available.
3.
Pardo E, Kim T, Wallrabe H, Zengeler K, Sagar V, Mingledorff G, et al.
bioRxiv
. 2024 Nov;
PMID: 39554169
Alterations in NADH and NADPH metabolism are associated with aging, cancer, and Alzheimer's Disease. Using 2P-FLIM imaging of the mitochondrial NAD(P)H in live human neurons and PS19 mouse brains, we...
4.
Hollis A, Lukens J
Immunol Rev
. 2024 Nov;
329(1):e13421.
PMID: 39523682
Epilepsy is a brain disorder characterized by recurrent seizures, which are brief episodes of abnormal electrical activity in the brain and involuntary movement that can lead to physical injury and...
5.
Stasiak K, Stevens A, Bolte A, Curley C, Perusina Lanfranca M, Lindsay R, et al.
Cancer Immunol Immunother
. 2024 Nov;
74(1):10.
PMID: 39487854
Patients with metastatic brain melanomas (MBM) experience shorter-lasting survival than patients with extracranial metastases, and this is associated with a higher fraction of dysfunctional CD8 T cells. The goal of...
6.
Babcock I, Sibley L, Labuzan S, Cowan M, Sethi I, Alemu S, et al.
PLoS Pathog
. 2024 Oct;
20(10):e1012006.
PMID: 39446964
Inflammasome activation is a robust innate immune mechanism that promotes inflammatory responses through the release of alarmins and leaderless cytokines, including IL-1α, IL-1β, and IL-18. Various stimuli, including infectious agents...
7.
Beiter R, Raghavan T, Suchocki O, Ennerfelt H, Rivet-Noor C, Merchak A, et al.
Res Sq
. 2024 Jun;
PMID: 38853911
Background: White matter loss is a well-documented phenomenon in Alzheimer's disease (AD) patients that has been recognized for decades. However, the underlying reasons for the failure of oligodendrocyte progenitor cells...
8.
Zengeler K, Lukens J
Trends Immunol
. 2024 Apr;
45(5):338-345.
PMID: 38616144
After decades of being overlooked, a recent wave of studies have explored the roles of microglia in brain health and disease. Microglia perform important physiological functions to set up and...
9.
Mangalmurti A, Lukens J
Brain Behav Immun
. 2024 Feb;
118:115-116.
PMID: 38408497
No abstract available.
10.
Fisher D, Sharifi K, Shah I, Gorick C, Breza V, Debski A, et al.
bioRxiv
. 2024 Feb;
PMID: 38352349
Background: Cerebral cavernous malformations (CCM) are vascular lesions within the central nervous system, consisting of dilated and hemorrhage-prone capillaries. CCMs can cause debilitating neurological symptoms, and surgical excision or stereotactic...