Thirumala-Devi Kanneganti
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Explore the profile of Thirumala-Devi Kanneganti including associated specialties, affiliations and a list of published articles.
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343
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34756
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Recent Articles
1.
Sharma B, Kanneganti T
Trends Immunol
. 2025 Feb;
PMID: 40016052
Lytic cell death is crucial for antimicrobial and antitumor immunity; however, unchecked pyroptosis drives pathology in sepsis. Wright et al. demonstrate that widespread cell death following pyroptosis is propagated by...
2.
Conradt B, Miao E, Yuan J, Kanneganti T, Stockwell B, Tsvetkov P, et al.
Dev Cell
. 2024 Oct;
59(19):2519-2522.
PMID: 39378837
Various types of cell death program are needed for cells to respond to changes in physiological conditions. In this collection of Voices, we asked scientists to tell the story behind...
3.
Nadella V, Kanneganti T
Curr Opin Immunol
. 2024 Sep;
91:102489.
PMID: 39340880
Inflammasomes are multiprotein signaling structures in the innate immune system that drive cell death and inflammatory responses. These protein complexes generally comprise an innate immune sensor, the adaptor protein ASC,...
4.
Malireddi R, Kanneganti T
Trends Immunol
. 2024 Sep;
45(10):732-734.
PMID: 39327205
Cancers hijack the nervous system for growth and spread. Thus, disrupting neuron-cancer crosstalk holds promise for blocking metastasis. Recently, Padmanaban et al. reported new therapeutic targets and showed that breast...
5.
Man S, Kanneganti T
Nat Cell Biol
. 2024 Sep;
26(9):1420-1433.
PMID: 39223376
Innate immunity, cell death and inflammation underpin many aspects of health and disease. Upon sensing pathogens, pathogen-associated molecular patterns or damage-associated molecular patterns, the innate immune system activates lytic, inflammatory...
6.
Malireddi R, Kanneganti T
Viruses
. 2024 Aug;
16(8).
PMID: 39205235
The innate immune system serves as the first line of defense against β-coronaviruses (β-CoVs), a family of viruses that includes SARS-CoV-2. Viral sensing via pattern recognition receptors triggers inflammation and...
7.
Sarkar R, Choudhury S, Kanneganti T
J Biol Chem
. 2024 Aug;
300(9):107676.
PMID: 39151726
Innate immunity is the body's first line of defense against disease, and regulated cell death is a central component of this response that balances pathogen clearance and inflammation. Cell death...
8.
Tweedell R, Hibler T, Kanneganti T
Curr Protoc
. 2024 Jul;
4(7):e1112.
PMID: 39073015
The innate immune system is the first line of host defense. Innate immune activation utilizes pattern recognition receptors to detect pathogens, pathogen-associated and damage-associated molecular patterns (PAMPs and DAMPs), and...
9.
10.
Briard B, Fontaine T, Kanneganti T, Gow N, Papon N
Cell Surf
. 2024 Jul;
11:100119.
PMID: 39022597
[This corrects the article DOI: 10.1016/j.tcsw.2021.100067.].