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Prabhash Nath Tripathi

Explore the profile of Prabhash Nath Tripathi including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 333
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Recent Articles
1.
Sharma P, Giri A, Tripathi P
Neurochem Res . 2024 Sep; 49(12):3208-3225. PMID: 39347854
Neurofilaments are structural proteins found in the cytoplasm of neurons, particularly in axons, providing structural support and stability to the axon. They consist of multiple subunits, including NF-H, NF-M, and...
2.
Tripathi P, Lodhi A, Rai S, Kumar Nandi N, Dumoga S, Yadav P, et al.
Degener Neurol Neuromuscul Dis . 2024 May; 14:47-74. PMID: 38784601
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and impaired daily functioning. While there is currently no cure for AD, several pharmacotherapeutic targets and...
3.
Siddiqui N, Saifi A, Chaudhary A, Tripathi P, Chaudhary A, Sharma A
Neurochem Res . 2023 Dec; 49(6):1427-1436. PMID: 38085406
Millions of people worldwide are currently afflicted with neurologic conditions like a seizure, depression, stress, Alzheimer's disease, Parkinson's disease, and Huntington's disease. However, the precise etiopathology of these diseases is...
4.
Saraf P, Tripathi P, Tripathi M, Tripathi A, Verma H, Waiker D, et al.
Bioorg Chem . 2022 Sep; 129:106147. PMID: 36126607
A novel series of 5,6-diphenyl-1,2,4-triazine-3-thiol derivatives were designed, synthesized, and screened for their inhibitory potential against COX-2 and 5-LOX enzymes. The compounds from the series have shown moderate to excellent...
5.
Sharma P, Tripathi A, Tripathi P, Singh S, Singh S, Shrivastava S
ACS Chem Neurosci . 2020 Aug; 11(17):2782. PMID: 32786328
No abstract available.
6.
Tripathi M, Sharma P, Tripathi A, Tripathi P, Srivastava P, Seth A, et al.
J Comput Aided Mol Des . 2020 Jun; 34(9):983-1002. PMID: 32488355
The cholinesterases are essential targets implicated in the pathogenesis of Alzheimer's disease (AD). In the present study, virtual screening and molecular docking are performed to identify the potential hits. Docking-post...
7.
Tripathi A, Choubey P, Sharma P, Seth A, Tripathi P, Tripathi M, et al.
Eur J Med Chem . 2019 Sep; 183:111707. PMID: 31561043
The diverse nature of Alzheimer's disease (AD) has prompted researchers to develop multi-functional agents. Herein, we have designed and synthesized molecular hybrids of 2-pyridylpiperazine and 5-phenyl-1,3,4-oxadiazoles. Biological activities of synthesized...
8.
Sharma P, Tripathi A, Tripathi P, Singh S, Singh S, Shrivastava S
ACS Chem Neurosci . 2019 Sep; 10(10):4361-4384. PMID: 31491074
Multitargeted hybrids of -benzylpiperidine and substituted 5-phenyl-1,3,4-oxadiazoles were designed, synthesized, and evaluated against Alzheimer's disease (AD). Tested compounds exhibited moderate to excellent inhibition against human acetylcholinesterase (hAChE), butyrylcholinesterase (hBChE), and...
9.
Srivastava P, Tripathi P, Sharma P, Shrivastava S
Bioorg Med Chem . 2019 Jul; 27(16):3650-3662. PMID: 31288978
Novel hybrids N-(4-phenoxybenzyl)aniline were designed, synthesized, and evaluated for their potential AChE inhibitory activity along with antioxidant potential. The inhibitory potential (IC) of synthesized analogs was evaluated against human cholinesterases...
10.
Mishra P, Sharma P, Tripathi P, Gupta S, Srivastava P, Seth A, et al.
Bioorg Chem . 2019 Jun; 89:103025. PMID: 31176239
The novel hybrids bearing 4-aminopyridine (4-AP) tethered with substituted 1,3,4-oxadiazole nucleus were designed, synthesized, and evaluated for their potential AChE inhibitory property along with significant antioxidant potential. The inhibitory potential...