Avanish Tripathi
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Explore the profile of Avanish Tripathi including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
196
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Recent Articles
1.
Gupta S, Behera A, Jain N, Tripathi A, Rishipathak D, Singh S, et al.
RSC Adv
. 2023 Sep;
13(38):26344-26356.
PMID: 37671344
Leading pathological markers of Alzheimer's disease (AD) include Acetylcholinesterase (AChE), Butyrylcholinesterase (BuChE), Amyloid beta (Aβ) and reactive oxygen species (ROS). Indole derivatives were identified and optimized to improve the potency...
2.
More U, Noolvi M, Kumar D, Tripathi A
Curr Drug Discov Technol
. 2023 Mar;
20(3):e290323215095.
PMID: 36999415
Background: BACE1 (beta-site amyloid precursor protein (APP) cleaving enzyme) is a key target for Alzheimer's disease research because it catalyses the rate-limiting step in the formation of amyloid protein (Aβ)....
3.
Gupta S, Behera A, Jain N, Kumar D, Tripathi A, Tripathi S, et al.
Pharmaceutics
. 2023 Jan;
15(1).
PMID: 36678724
As acetylcholinesterase (AChE) plays a crucial role in advancing Alzheimer's disease (AD), its inhibition is a promising approach for treating AD. Sulindac is an NSAID of the aryl alkanoic acid...
4.
Saraf P, Tripathi P, Tripathi M, Tripathi A, Verma H, Waiker D, et al.
Bioorg Chem
. 2022 Sep;
129:106147.
PMID: 36126607
A novel series of 5,6-diphenyl-1,2,4-triazine-3-thiol derivatives were designed, synthesized, and screened for their inhibitory potential against COX-2 and 5-LOX enzymes. The compounds from the series have shown moderate to excellent...
5.
Mujwar S, Tripathi A
J Mol Model
. 2022 Jun;
28(7):193.
PMID: 35716240
Fungal infections in humans are responsible for mild to severe infections resulting in systemic effects that cause a large amount of mortality. Invasive fungal infections are having similar symptomatic effects...
6.
Choubey P, Tripathi A, Tripathi M, Seth A, Shrivastava S
Bioorg Chem
. 2021 May;
111:104922.
PMID: 33945941
Novel N-Benzylpyrrolidine hybrids were designed, synthesized, and tested against multiple in-vitro and in-vivo parameters. Among all the synthesized molecules, 8f and 12f showed extensive inhibition against beta-secretase-1 (hBACE-1), human acetylcholinesterase...
7.
Choubey P, Tripathi A, Sharma P, Shrivastava S
Bioorg Med Chem
. 2020 Oct;
28(22):115721.
PMID: 33007563
Multitarget molecular hybrids of N-benzyl pyrrolidine derivatives were designed, synthesized, and biologically evaluated for the treatment of Alzheimer's disease (AD). Among the synthesized compounds, 4k and 4o showed balanced enzyme...
8.
Sharma P, Tripathi A, Tripathi P, Singh S, Singh S, Shrivastava S
ACS Chem Neurosci
. 2020 Aug;
11(17):2782.
PMID: 32786328
No abstract available.
9.
Tripathi M, Sharma P, Tripathi A, Tripathi P, Srivastava P, Seth A, et al.
J Comput Aided Mol Des
. 2020 Jun;
34(9):983-1002.
PMID: 32488355
The cholinesterases are essential targets implicated in the pathogenesis of Alzheimer's disease (AD). In the present study, virtual screening and molecular docking are performed to identify the potential hits. Docking-post...
10.
Tripathi A, Choubey P, Sharma P, Seth A, Saraf P, Shrivastava S
Bioorg Chem
. 2019 Dec;
95:103506.
PMID: 31887472
Thirty ferulic acid-based 1,3,4-oxadiazole molecular hybrids were designed, synthesized, and screened them for multifunctional inhibitory potential against acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and beta-secretase-1 (BACE-1). Compound 6j was the most potent...