Pooja Shivshankar
Overview
Explore the profile of Pooja Shivshankar including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
1048
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Recent Articles
1.
Shivshankar P, Mueller-Ortiz S, Domozhirov A, Bi W, Collum S, Doursout M, et al.
Respir Res
. 2025 Feb;
26(1):68.
PMID: 40016722
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced coronavirus disease 2019 (COVID-19) pandemic has challenged the current understanding of the complement cascade mechanisms of host immune responses during infection-induced nonresolvable...
2.
Shadid A, Rich H, DeVaughn H, Domozhirov A, Doursout M, Weng-Mills T, et al.
Front Cell Infect Microbiol
. 2025 Jan;
14:1479801.
PMID: 39760094
Interstitial lung disease (ILD) is characterized by chronic inflammation and scarring of the lungs, of which idiopathic pulmonary fibrosis (IPF) is the most devastating pathologic form. Idiopathic pulmonary fibrosis pathogenesis...
3.
DeVaughn H, Rich H, Shadid A, Vaidya P, Doursout M, Shivshankar P
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684535
Originally discovered in the 1890s, the complement system has traditionally been viewed as a "compliment" to the body's innate and adaptive immune response. However, emerging data have shown that the...
4.
Wang R, Lee J, Kim J, Xiong F, Hasani L, Shi Y, et al.
Nat Microbiol
. 2023 Mar;
8(4):679-694.
PMID: 36959507
Some viruses restructure host chromatin, influencing gene expression, with implications for disease outcome. Whether this occurs for SARS-CoV-2, the virus causing COVID-19, is largely unknown. Here we characterized the 3D...
5.
Jyothula S, Peters A, Liang Y, Bi W, Shivshankar P, Yau S, et al.
EBioMedicine
. 2022 Nov;
86:104351.
PMID: 36375315
Background: Coronavirus Disease 2019 (COVID-19) can lead to the development of acute respiratory distress syndrome (ARDS). In some patients with non-resolvable (NR) COVID-19, lung injury can progress rapidly to the...
6.
Wilson C, Mertens T, Shivshankar P, Bi W, Collum S, Wareing N, et al.
JCI Insight
. 2022 Apr;
7(10).
PMID: 35420997
Idiopathic pulmonary fibrosis (IPF) is a fatal disease with limited treatment options. The role of the developmental transcription factor Sine oculis homeobox homolog 1 (SIX1) in the pathophysiology of lung...
7.
Shivshankar P, Karmouty-Quintana H, Mills T, Doursout M, Wang Y, Czopik A, et al.
Inflammation
. 2022 Mar;
45(4):1430-1449.
PMID: 35320469
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a global pandemic with severe socioeconomic effects. Immunopathogenesis of COVID-19 leads to acute...
8.
Wang R, Lee J, Xiong F, Kim J, Hasani L, Yuan X, et al.
bioRxiv
. 2021 Jul;
PMID: 34312624
SARS-CoV-2 has made >190-million infections worldwide, thus it is pivotal to understand the viral impacts on host cells. Many viruses can significantly alter host chromatin , but such roles of...
9.
Shivshankar P, Fekry B, Eckel-Mahan K, Wetsel R
Front Cell Infect Microbiol
. 2020 Sep;
10:418.
PMID: 32923410
Mammalian species contain an internal circadian (i.e., 24-h) clock that is synchronized to the day and night cycles. Large epidemiological studies, which are supported by carefully controlled studies in numerous...
10.
Shivshankar P, Li Y, Mueller-Ortiz S, Wetsel R
FASEB J
. 2020 Apr;
34(6):7540-7560.
PMID: 32301538
The vascular endothelium has been discovered in the past several years to be important in shaping the cellular immune response. During the immune response the vascular endothelium is constantly perturbed...