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Inflammation

'Inflammation' is a peer-reviewed scientific journal that focuses on the study of inflammation and its role in various diseases and conditions. It publishes original research articles, reviews, and commentaries that explore the mechanisms, diagnosis, treatment, and prevention of inflammation-related disorders. The journal serves as a valuable resource for researchers, clinicians, and healthcare professionals interested in understanding and managing inflammation.
Details
Abbr. Inflammation
Start 1975
End Continuing
Frequency Bimonthly
p-ISSN 0360-3997
e-ISSN 1573-2576
Country United States
Language English
Specialties Pathology
Allergy & Immunology
Metrics
h-index / Ranks: 4506 78
SJR / Ranks: 3278 1090
CiteScore / Ranks: 1874 8.80
JIF / Ranks: 1521 5.1
Recent Articles
1.
Microglial Annexin A3 Downregulation Alleviates Ischemic Injury by Inhibiting NF-κB/NLRP3-mediated Inflammation
Zhang Z, Zhang M, Li D, Shu R, Pan Q, Zou W, et al.
Inflammation . 2025 Mar; PMID: 40087252
Microglial inflammation is a hallmark of ischemic stroke. Annexin A3 (ANXA3) is expressed in microglia and plays a detrimental role in stroke. However, the role of ANXA3 in microglial inflammation...
2.
Toll Like Receptors Promote High Glucose-Induced Vascular Endothelial Cell Dysfunction by Regulating Neutrophil Extracellular Traps Formation
Wu S, Chen Y, Jin X, Yu J, Chen X, Wan T
Inflammation . 2025 Mar; PMID: 40087251
Diabetic retinopathy (DR) is a major cause of blindness globally. Neutrophils and neutrophil extracellular traps (NETs) are believed to play a role in the development of DR. However, the specific...
3.
TXM-CB13 Improves the Intestinal Mucosal Barrier and Alleviates Colitis by Inhibiting the ROS/TXNIP/TRX/NLRP3 and TLR4/MyD88/NF-κB/NLRP3 Pathways
Cao R, Zhou J, Liu J, Wang Y, Dai Y, Jiang Y, et al.
Inflammation . 2025 Mar; PMID: 40085192
The activation of inflammasomes (NLRP3 and NLRP1) is central to the pathogenesis of inflammatory bowel disease (IBD). Here we examined the protective effects of a thioredoxin-mimetic peptide CB13 (TXM-CB13), known...
4.
Canagliflozin Attenuates Podocyte Inflammatory Injury through Suppressing the TXNIP/NLRP3 Signaling Pathway in Diabetic Kidney Disease Mice
Li S, Wang J, Chen Y, Cheng Y, Wang Y, Xu N, et al.
Inflammation . 2025 Mar; PMID: 40067577
Diabetic kidney disease (DKD), a leading cause of end-stage renal disease (ESRD), poses a serious threat to global health. Aseptic inflammation and pyroptosis of podocytes are crucial factors contributing to...
5.
"The Ameliorative Effect of Interleukin-17A Neutralization on Doxorubicin-Induced Cardiotoxicity by Modulating the NF-κB/NLRP3/Caspase-1/IL-1β Signaling Pathway in Rats"
Hassen M, Mousa N, Radwan S, Gabre R
Inflammation . 2025 Mar; PMID: 40064794
Doxorubicin (DOX) is used as a chemotherapeutic drug for treating cancer. Nevertheless, it causes damage to the heart by activating inflammatory pathways, resulting in cardiotoxicity. Imbalance in cytokine production is...
6.
Substance P Augments Chemokine Production by Staphylococcus aureus Infected Murine Osteoclasts
Sipprell S, Krueger Q, Mills E, Marriott I, Johnson M
Inflammation . 2025 Mar; PMID: 40056352
Staphylococcal osteomyelitis is a serious infection of the bone and joints characterized by progressive inflammatory tissue damage and leukocyte recruitment leading to net bone loss. Resident bone cells are capable...
7.
USP5 Deletion Inhibits KD Serum Induced-Human Coronary Artery Endothelial Cell Dysfunction by Regulating the NFATC1/TLR4-Mediated NF-κB Signaling Pathway in Kawasaki Disease
Yao L, Lai Y, Li H, Chen S, Yu X, Zhou N, et al.
Inflammation . 2025 Mar; PMID: 40053057
Kawasaki disease (KD) is an acute febrile illness characterized by systemic vasculitis, especially in coronary arteries. Previous studies have indicated that nuclear factor of activated T cells, cytoplasmic 1 (NFATC1,...
8.
VASP Knockdown Ameliorates Lipopolysaccharide-Induced Acute Lung Injury with Inhibition of M1 Macrophage Polarization Through the cGMP-PKG Signaling Pathway
Tang J, Ding Y, Chen W, Shi J, Zhang C, Zhao X, et al.
Inflammation . 2025 Mar; PMID: 40045018
Alveolar macrophage (AM) polarization plays a pivotal role in the inflammatory response during acute lung injury (ALI). As reported previously, vasodilator-stimulated phosphoprotein (VASP) may function as an anti-inflammatory agent in...
9.
Baicalein Reduces Pyroptosis of Acinar Cells in Hyperlipidemic Acute Pancreatitis by Inhibiting M1 Polarization of Macrophages via the HMGB1/TLR4/NLRP3 Pathway
Wang X, Zhou Y, Liu Y, Mo T, Chen Z, Zhang Y, et al.
Inflammation . 2025 Mar; PMID: 40042793
Previous studies have shown that baicalein (BAI) can reduce pyroptosis of pancreatic acinar cells (PACs) in hyperlipidemic acute pancreatitis (HAP). This study aimed to elucidate the potential molecular mechanism of...
10.
DNAJB2 Attenuates Rosacea Skin Inflammation and Angiogenesis by Inhibiting the Endoplasmic Reticulum Stress-mediated TLR2/Myd88/NF-κB pathway
Qing Y, Wu J, Xu B, Xu Z, Ye S, Wang Y, et al.
Inflammation . 2025 Mar; PMID: 40035989
Endoplasmic reticulum stress (ERS) has recently been proposed as a core factor in the pathogenesis and aggravation of rosacea. The roles of ERS-related genes in rosacea are largely unknown and...