Ponniah Selvakumar
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Explore the profile of Ponniah Selvakumar including associated specialties, affiliations and a list of published articles.
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39
Citations
400
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Recent Articles
1.
Musi E, Schwartz G, Yoo J, Odelberg S, Li D, Bonner M, et al.
Oncotarget
. 2019 Jul;
10(43):4424-4436.
PMID: 31320995
Uveal melanoma is a rare but often lethal malignancy and is the leading cause of death due to an ophthalmic condition. Uveal melanoma is often diagnosed at a late stage...
2.
Srinivasan A, Thangavel C, Liu Y, Shoyele S, Den R, Selvakumar P, et al.
Mol Carcinog
. 2015 May;
55(5):743-56.
PMID: 25968914
Triple negative breast cancer (TNBC) is characterized by a lack in estrogen, progesterone, and epidermal growth factor 2 receptors. TNBC exhibits most of the characteristics of basal-like and claudin-low breast...
3.
Selvakumar P, Owens T, David J, Petrelli N, Christensen B, Lakshmikuttyamma A, et al.
Epigenetics
. 2014 Jan;
9(4):579-86.
PMID: 24452105
The Na,K-ATPase or sodium pump carries out the coupled extrusion of Na(+) and uptake of K(+) across the plasma membranes of cells of most higher eukaryotes. We have shown earlier...
4.
Selvakumar P, Kumar S, Dimmock J, Sharma R
Atlas Genet Cytogenet Oncol Haematol
. 2012 Sep;
15(7):570-575.
PMID: 22977462
No abstract available.
5.
Das U, Sakagami H, Chu Q, Wang Q, Kawase M, Selvakumar P, et al.
Bioorg Med Chem Lett
. 2010 Jan;
20(3):912-7.
PMID: 20064715
A number of N-4-(2-aminoethoxy)phenylcarbonyl derivatives of various 3,5-bis(benzylidene)-4-piperidones 2-5 demonstrated noteworthy cytotoxic potencies towards human HL-60 leukemic cells as well as human HSC-2 and HSC-4 squamous cell carcinomas. In general,...
6.
Charavaryamath C, Lemieux H, Suri S, Selvakumar P, Sharma R, Singh B
Exp Lung Res
. 2009 Nov;
35(9):729-47.
PMID: 19916857
The role of N-myristoyltransferase and calcineurin is well established in signaling pathways. However, there are no data on their expression and activities in normal and inflamed lungs. The mechanisms of...
7.
Das S, Das U, Selvakumar P, Sharma R, Balzarini J, De Clercq E, et al.
ChemMedChem
. 2009 Oct;
4(11):1831-40.
PMID: 19802855
A series of 3,5-bis(benzylidene)-4-piperidones 3 were converted into the corresponding 3,5-bis(benzylidene)-1-phosphono-4-piperidones 5 via diethyl esters 4. The analogues in series 4 and 5 displayed marked growth inhibitory properties toward human...
8.
Selvakumar P, Lakshmikuttyamma A, Sharma R
J Biomed Biotechnol
. 2009 Sep;
2009:907614.
PMID: 19746168
Protein N-myristoylation is a lipidic modification which refers to the covalent attachment of myristate, a 14-carbon saturated fatty acid, to the N-terminal glycine residue of a number of mammalian, viral,...
9.
Selvakumar P, Lakshmikuttyamma A, Das U, Pati H, Dimmock J, Sharma R
Mol Cancer
. 2009 Aug;
8:65.
PMID: 19703310
Methionine aminopeptidase 2 (MetAP2) is a bifunctional protein that plays a critical role in the regulation of post-translational processing and protein synthesis. MetAP2 is overexpressed in human colon cancer. In...
10.
Zuo Y, Selvakumar P, Sharma R
Mol Cell Biochem
. 2009 Jul;
333(1-2):73-82.
PMID: 19629647
Calcineurin (CaN) is a member of ser/thr protein phosphatase family. Earlier, we have reported that CaN is present in all eye tissues, although the activity and protein expression varied (Seitz...