Ashakumary Lakshmikuttyamma
Overview
Explore the profile of Ashakumary Lakshmikuttyamma including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
516
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Recent Articles
1.
Badgeley A, Anwar H, Modi K, Murphy P, Lakshmikuttyamma A
Biochim Biophys Acta Rev Cancer
. 2020 Dec;
1875(1):188494.
PMID: 33346129
Bacteria present in probiotics, particularly the common Lactobacillus and Bifidobacterium microbes, have been found to induce anti-cancer action by enhancing cancer cell apoptosis and protecting against oxidative stress. Probiotics supplements...
2.
Modi K, Lawson S, Chen G, Tumuluri D, Rekhtman I, Kurtz M, et al.
Int J Mol Sci
. 2020 Aug;
21(16).
PMID: 32806551
Curcumin has been well studied for its anti-oxidant, anti-inflammatory, and anti-cancer action. Its potential as a therapy is limited due to its low bioavailability and rapid metabolism. To overcome these...
3.
Selvakumar P, Badgeley A, Murphy P, Anwar H, Sharma U, Lawrence K, et al.
Nutrients
. 2020 Mar;
12(3).
PMID: 32183060
Breast cancer is a common cancer that occurs due to different epigenetic alterations and genetic mutations. Various epidemiological studies have demonstrated an inverse correlation between breast cancer incidence and flavonoid...
4.
Kundur S, Prayag A, Selvakumar P, Nguyen H, McKee L, Cruz C, et al.
J Cell Physiol
. 2018 Nov;
234(7):11103-11118.
PMID: 30478904
Women with the breast cancer type 1 susceptibility protein (BRCA1) mutation and loss of BRCA1 expression are reported to have an increased risk of triple-negative breast cancer (TNBC). Targeting BRCA1...
5.
Perepelyuk M, Maher C, Lakshmikuttyamma A, Shoyele S
Int J Nanomedicine
. 2016 Aug;
11:3533-44.
PMID: 27555773
MicroRNAs (miRNAs) are potentially attractive candidates for cancer therapy. However, their therapeutic application is limited by lack of availability of an efficient delivery system to stably deliver these potent molecules...
6.
Dim N, Perepelyuk M, Gomes O, Thangavel C, Liu Y, Den R, et al.
J Nanobiotechnology
. 2015 Sep;
13:61.
PMID: 26410728
Background: siRNAs have a high potential for silencing critical molecular pathways that are pathogenic. Nevertheless, their clinical application has been limited by a lack of effective and safe nanotechnology-based delivery...
7.
Srinivasan A, Thangavel C, Liu Y, Shoyele S, Den R, Selvakumar P, et al.
Mol Carcinog
. 2015 May;
55(5):743-56.
PMID: 25968914
Triple negative breast cancer (TNBC) is characterized by a lack in estrogen, progesterone, and epidermal growth factor 2 receptors. TNBC exhibits most of the characteristics of basal-like and claudin-low breast...
8.
Selvakumar P, Owens T, David J, Petrelli N, Christensen B, Lakshmikuttyamma A, et al.
Epigenetics
. 2014 Jan;
9(4):579-86.
PMID: 24452105
The Na,K-ATPase or sodium pump carries out the coupled extrusion of Na(+) and uptake of K(+) across the plasma membranes of cells of most higher eukaryotes. We have shown earlier...
9.
Srinivasan A, Lakshmikuttyamma A, Shoyele S
Mol Pharm
. 2013 Aug;
10(9):3275-84.
PMID: 23915336
The inability to deliver MAbs to intracellular targets still remains a limitation to their application in cancer therapy and diagnosis. Selective targeting of MAbs to oncoproteins in cancer cells while...
10.
Selvakumar P, Lakshmikuttyamma A, Sharma R
J Biomed Biotechnol
. 2009 Sep;
2009:907614.
PMID: 19746168
Protein N-myristoylation is a lipidic modification which refers to the covalent attachment of myristate, a 14-carbon saturated fatty acid, to the N-terminal glycine residue of a number of mammalian, viral,...