Phillip B Carpenter
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Explore the profile of Phillip B Carpenter including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
2041
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0
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Recent Articles
1.
Carpenter P, Poliak A, Wang L, Ownby A, Hsieh P
Med Educ
. 2020 Mar;
54(5):449-450.
PMID: 32175609
No abstract available.
2.
Feldman S, Wuerffel R, Achour I, Wang L, Carpenter P, Kenter A
J Immunol
. 2017 Feb;
198(6):2434-2444.
PMID: 28159901
In B lymphocytes, Ig class switch recombination (CSR) is induced by activation-induced cytidine deaminase, which initiates a cascade of events leading to DNA double-strand break formation in switch (S) regions....
3.
Wagner E, Carpenter P
Nat Rev Mol Cell Biol
. 2012 Jan;
13(2):115-26.
PMID: 22266761
Histone side chains are post-translationally modified at multiple sites, including at Lys36 on histone H3 (H3K36). Several enzymes from yeast and humans, including the methyltransferases SET domain-containing 2 (Set2) and...
4.
Lucio-Eterovic A, Carpenter P
Transcription
. 2011 Sep;
2(4):158-161.
PMID: 21922056
The three components of the mammalian nuclear SET domain containing protein (NSD) family have been implicated in multiple diseases and cancers, but very little is known about their mechanisms of...
5.
Lucio-Eterovic A, Singh M, Gardner J, Veerappan C, Rice J, Carpenter P
Proc Natl Acad Sci U S A
. 2010 Sep;
107(39):16952-7.
PMID: 20837538
The NSD (nuclear receptor-binding SET domain protein) family encodes methyltransferases that are important in multiple aspects of development and disease. Perturbations in NSD family members can lead to Sotos syndrome...
6.
Dou H, Huang C, Singh M, Carpenter P, Yeh E
Mol Cell
. 2010 Aug;
39(3):333-45.
PMID: 20705237
The replication protein A complex (RPA) plays a crucial role in DNA replication and damage response. However, it is not known whether this complex is regulated by the SUMOylation pathway....
7.
Rai R, Zheng H, He H, Luo Y, Multani A, Carpenter P, et al.
EMBO J
. 2010 Jul;
29(15):2598-610.
PMID: 20588252
Repair of DNA double-stranded breaks (DSBs) is crucial for the maintenance of genome stability. DSBs are repaired by either error prone non-homologous end-joining (NHEJ) or error-free homologous recombination. NHEJ precedes...
8.
Houston S, McManus K, Adams M, Sims J, Carpenter P, Hendzel M, et al.
J Biol Chem
. 2008 May;
283(28):19478-88.
PMID: 18480059
Histone-modifying enzymes play a critical role in modulating chromatin dynamics. In this report we demonstrate that one of these enzymes, PR-Set7, and its corresponding histone modification, the monomethylation of histone...
9.
Adams M, Carpenter P
Cell Div
. 2006 Sep;
1:19.
PMID: 16945145
To maintain genomic stability and ensure the fidelity of chromosomal transmission, cells respond to various forms of genotoxic stress, including DNA double-stranded breaks (DSBs), through the activation of DNA damage...
10.
Morales J, Franco S, Murphy M, Bassing C, Mills K, Adams M, et al.
Proc Natl Acad Sci U S A
. 2006 Feb;
103(9):3310-5.
PMID: 16492765
p53-binding protein 1 (53BP1) participates in the cellular response to DNA double-stranded breaks where it associates with various DNA repair/cell cycle factors including the H2AX histone variant. Mice deficient for...