Philippe St-Pierre
Overview
Explore the profile of Philippe St-Pierre including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
492
Followers
0
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Recent Articles
1.
Fernandes M, Aristizabal-Henao J, Marvyn P, MHiri I, Wiens M, Hoang M, et al.
Mol Metab
. 2024 Jan;
81:101887.
PMID: 38280449
Objective: Lipotoxic injury from renal lipid accumulation in obesity and type 2 diabetes (T2D) is implicated in associated kidney damage. However, models examining effects of renal ectopic lipid accumulation independent...
2.
Daniel N, Nachbar R, Tran T, Ouellette A, Varin T, Cotillard A, et al.
Nat Commun
. 2022 Mar;
13(1):1343.
PMID: 35292630
Meta-analyses suggest that yogurt consumption reduces type 2 diabetes incidence in humans, but the molecular basis of these observations remains unknown. Here we show that dietary yogurt intake preserves whole-body...
3.
Choi B, Daniel N, Houde V, Ouellette A, Marcotte B, Varin T, et al.
Nat Commun
. 2021 Jun;
12(1):3377.
PMID: 34099716
Animal models of human diseases are classically fed purified diets that contain casein as the unique protein source. We show that provision of a mixed protein source mirroring that found...
4.
Daniel N, Perazza L, Varin T, Trottier J, Marcotte B, St-Pierre P, et al.
Am J Physiol Gastrointest Liver Physiol
. 2021 Apr;
320(6):G1014-G1033.
PMID: 33881354
Selecting the most relevant control diet is of critical importance for metabolic and intestinal studies in animal models. Chow and LF-purified diet differentially impact metabolic and gut microbiome outcomes resulting...
5.
Valle M, Mitchell P, Pilon G, St-Pierre P, Varin T, Richard D, et al.
J Nutr
. 2021 Apr;
151(5):1175-1189.
PMID: 33851198
Background: Cholecalciferol (D3) may improve inflammation, and thus provide protection from cardiometabolic diseases (CMD), although controversy remains. Omega-3 fatty acids (ω-3FA) may also prevent the development of CMD, but the...
6.
Perazza L, Mitchell P, Lizotte F, Jensen B, St-Pierre P, Trottier J, et al.
FASEB J
. 2021 Apr;
35(5):e21559.
PMID: 33835594
Diabetic nephropathy (DN) remains the major cause of end-stage renal disease (ESRD). We used high-fat/high-sucrose (HFHS)-fed LDLr /ApoB mice with transgenic overexpression of IGFII in pancreatic β-cells (LRKOB100/IGFII) as a...
7.
Choi B, Varin T, St-Pierre P, Pilon G, Tremblay A, Marette A
Food Chem Toxicol
. 2020 Nov;
146:111832.
PMID: 33129933
The dramatic rise in the global occurrence of obesity and associated diseases calls for new strategies to promote weight loss. However, while the beneficial effects of weight loss are well...
8.
Valle M, St-Pierre P, Pilon G, Marette A
Nutrients
. 2020 Aug;
12(8).
PMID: 32751772
While the detrimental effect of refined sugars on health has been the subject of many investigations, little is known about the long-term impact of natural sweeteners on metabolic disorders. In...
9.
Morissette A, Kropp C, Songpadith J, Moreira R, Costa J, Marine-Casado R, et al.
Am J Physiol Endocrinol Metab
. 2020 Apr;
318(6):E965-E980.
PMID: 32228321
Blueberry consumption can prevent obesity-linked metabolic diseases, and it has been proposed that the polyphenol content of blueberries may contribute to these effects. Polyphenols have been shown to favorably impact...
10.
Shum M, Houde V, Bellemare V, Moreira R, Bellmann K, St-Pierre P, et al.
J Biol Chem
. 2019 Jun;
294(32):12250-12260.
PMID: 31243102
mTOR complex 1 (mTORC1) and p70 S6 kinase (S6K1) are both involved in the development of obesity-linked insulin resistance. Recently, we showed that the S6K1 inhibitor PF-4708671 (PF) increases insulin...