Patricia L Mitchell
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Explore the profile of Patricia L Mitchell including associated specialties, affiliations and a list of published articles.
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46
Citations
518
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Recent Articles
1.
Maltais-Payette I, Bourgault J, Gauthier M, Biertho L, Marceau S, Julien F, et al.
Physiol Rep
. 2025 Jan;
13(3):e70171.
PMID: 39868884
Metabolic dysfunction-associated steatotic liver disease (MASLD) describes liver diseases caused by the accumulation of triglycerides in hepatocytes (steatosis) as well as the resulting inflammation and fibrosis. Previous studies have demonstrated...
2.
Mitchell P, Pilon G, Bazinet L, Gagnon C, Weisnagel S, Jacques H, et al.
Appl Physiol Nutr Metab
. 2024 Aug;
49(11):1600-1605.
PMID: 39137439
People use dietary supplements to offset nutritional deficiencies and manage metabolic dysfunction. While the beneficial effect of fish proteins on glucose homeostasis is well established, the ability of fish peptides...
3.
Gobeil E, Bourgault J, Mitchell P, Houessou U, Gagnon E, Girard A, et al.
Eur Heart J
. 2024 Jan;
45(9):707-721.
PMID: 38243829
Background And Aims: RNA-based, antibody-based, and genome editing-based therapies are currently under investigation to determine if the inhibition of angiopoietin-like protein-3 (ANGPTL3) could reduce lipoprotein-lipid levels and atherosclerotic cardiovascular disease...
4.
Gagnon E, Paulin A, Mitchell P, Arsenault B
Atherosclerosis
. 2023 Nov;
386:117371.
PMID: 38029505
Background And Aims: Individuals with a higher abdominal adipose tissue accumulation are at higher risk of developing cardiometabolic diseases. For a given body mass index (BMI), women typically present lower...
5.
Gagnon E, Manikpurage H, Mitchell P, Girard A, Gobeil E, Bourgault J, et al.
iScience
. 2023 Jul;
26(7):107127.
PMID: 37456853
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent disease with no specific drug therapy. High-throughput metabolomics present an unprecedented opportunity to identify biomarkers and potentially causal risk factors for...
6.
Gagnon E, Girard A, Gobeil E, Bourgault J, Couture C, Mitchell P, et al.
iScience
. 2023 Apr;
26(4):106376.
PMID: 37013190
Genome-wide association studies (GWAS) have identified hundreds of genetic variants associated with body weight but the biological relevance of most remains unexplored. Given the critical role of the brain in...
7.
Daoust L, Choi B, Agrinier A, Varin T, Ouellette A, Mitchell P, et al.
Gut
. 2023 Mar;
72(5):896-905.
PMID: 36881441
Objective: Faecal microbiota transplantation (FMT) in germ-free (GF) mice is a common approach to study the causal role of the gut microbiota in metabolic diseases. Lack of consideration of housing...
8.
Daniel N, Le Barz M, Mitchell P, Varin T, Julien I, Farabos D, et al.
Function (Oxf)
. 2023 Feb;
4(2):zqac069.
PMID: 36778746
We compared endogenous ω-3 PUFA production to supplementation for improving obesity-related metabolic dysfunction. Fat-1 transgenic mice, who endogenously convert exogenous ω-6 to ω-3 PUFA, and wild-type littermates were fed a...
9.
Bourgault J, Abner E, Manikpurage H, Pujol-Gualdo N, Laisk T, Gobeil E, et al.
Gastroenterology
. 2023 Feb;
164(6):953-965.e3.
PMID: 36736436
Background & Aims: Acute pancreatitis (AP) is a complex disease and the leading cause of gastrointestinal disease-related hospital admissions. Few therapeutic options exist for AP prevention. Blood proteins with causal...
10.
Gagnon E, Mitchell P, Manikpurage H, Abner E, Taba N, Esko T, et al.
J Transl Med
. 2023 Jan;
21(1):60.
PMID: 36717893
Features of the gut microbiota have been associated with several chronic diseases and longevity in preclinical models as well as in observational studies. Whether these relations underlie causal effects in...