Philippe Guillaume
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Explore the profile of Philippe Guillaume including associated specialties, affiliations and a list of published articles.
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119
Citations
4114
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Recent Articles
1.
Semilietof A, Stefanidis E, Gray-Gaillard E, Pujol J, DEsposito A, Reichenbach P, et al.
J Immunother Cancer
. 2025 Jan;
12(12.
PMID: 39794936
Background: The adoptive cell transfer (ACT) of T cell receptor (TCR)-engineered T cells targeting the HLA-A2-restricted epitope NY-ESO-1 (A2/NY) has yielded important clinical responses against several cancers. A variety of...
2.
Carre A, Shankland R, Guillaume P, Duclos J, El-Jor C, Pellissier S, et al.
Front Psychol
. 2024 Sep;
15:1261994.
PMID: 39309147
Background: Awareness of one's own states is a particularly important part of cognition and emotion regulation. Recently, the concept of alexisomia has been used to refer to lack of awareness...
3.
Guillaume P, Rupp T, Froget G, Goineau S
Int J Mol Sci
. 2024 Sep;
25(17).
PMID: 39273201
Psoriasis is a chronic inflammatory skin disorder characterized by keratinocyte hyperproliferation, inflammation, and aberrant differentiation. Imiquimod-induced psoriasis in rodent models has been widely used to study the pathogenesis of the...
4.
Lariosa-Willingham K, Leonoudakis D, Simon F, Walker K, Guillaume P, Warren L, et al.
BMC Res Notes
. 2023 Nov;
16(1):348.
PMID: 38007440
Objectives: Animal models of skin disease are used to evaluate therapeutics to alleviate disease. One common clinical dermatological complaint is pruritus (itch), but there is a lack of standardization in...
5.
Schmidt J, Chiffelle J, Perez M, Magnin M, Bobisse S, Arnaud M, et al.
Nat Commun
. 2023 Jun;
14(1):3188.
PMID: 37280206
The success of cancer immunotherapy depends in part on the strength of antigen recognition by T cells. Here, we characterize the T cell receptor (TCR) functional (antigen sensitivity) and structural...
6.
Genolet R, Bobisse S, Chiffelle J, Arnaud M, Petremand R, Queiroz L, et al.
Cell Rep Methods
. 2023 May;
3(4):100459.
PMID: 37159666
T cell receptor (TCR) technologies, including repertoire analyses and T cell engineering, are increasingly important in the clinical management of cellular immunity in cancer, transplantation, and other immune diseases. However,...
7.
Racle J, Guillaume P, Schmidt J, Michaux J, Larabi A, Lau K, et al.
Immunity
. 2023 Apr;
56(6):1359-1375.e13.
PMID: 37023751
CD4 T cells orchestrate the adaptive immune response against pathogens and cancer by recognizing epitopes presented on class II major histocompatibility complex (MHC-II) molecules. The high polymorphism of MHC-II genes...
8.
Fritah H, Graciotti M, Lai-Lai Chiang C, Huguenin-Bergenat A, Petremand R, Ahmed R, et al.
iScience
. 2023 Mar;
26(4):106288.
PMID: 36950115
Antigen selection and prioritization represent crucial determinants of vaccines' efficacy. Here, we compare two personalized dendritic cell-based vaccination strategies using whole-tumor lysate or neoantigens. Data in mouse and in cancer...
9.
Gfeller D, Schmidt J, Croce G, Guillaume P, Bobisse S, Genolet R, et al.
Cell Syst
. 2023 Jan;
14(1):72-83.e5.
PMID: 36603583
The recognition of pathogen or cancer-specific epitopes by CD8 T cells is crucial for the clearance of infections and the response to cancer immunotherapy. This process requires epitopes to be...
10.
Baumgaertner P, Schmidt J, Costa-Nunes C, Bordry N, Guillaume P, Luescher I, et al.
Front Immunol
. 2022 Aug;
13:973986.
PMID: 36032094
Recruitment and activation of CD8 T cells occur through specific triggering of T cell receptor (TCR) by peptide-bound human leucocyte antigen (HLA) ligands. Within the generated trimeric TCR-peptide:HLA complex, the...