Peter R Holt
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Explore the profile of Peter R Holt including associated specialties, affiliations and a list of published articles.
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45
Citations
1458
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Recent Articles
1.
Holt P, Altayar O, Alpers D
Nutrients
. 2023 Nov;
15(21).
PMID: 37960347
Body mass index (BMI) is a function of weight and height, but changing height has not been emphasized. Using the Framingham Heart Study with 5 decades of data on anthropomorphic...
2.
McDowell S, Milette S, Dore S, Yu M, Sorin M, Wilson L, et al.
J Exp Med
. 2023 May;
220(8).
PMID: 37166450
Obesity is characterized by chronic systemic inflammation and enhances cancer metastasis and mortality. Obesity promotes breast cancer metastasis to lung in a neutrophil-dependent manner; however, the upstream regulatory mechanisms of...
3.
Da Rosa J, Aleman J, Mohabir J, Liang Y, Breslow J, Holt P
OMICS
. 2022 Dec;
26(12):660-670.
PMID: 36454164
Obesity has reached epidemic proportions in the United States, but little is known about the mechanisms of weight gain and weight loss. Integration of omics data is becoming a popular...
4.
Bosch B, Holt P
J Pediatr Gastroenterol Nutr
. 2022 Oct;
76(2):120-122.
PMID: 36245075
The link between bread and wheat products and celiac disease was first recognized by Willem Dicke in the 1930s through clinical observations of his child patients. The role of gluten...
5.
Aleman J, Henderson W, Walker J, Ronning A, Jones D, Walter P, et al.
J Clin Transl Sci
. 2021 Aug;
5(1):e143.
PMID: 34422323
Introduction: Non-alcoholic fatty liver disease (NAFLD) is an increasing cause of chronic liver disease that accompanies obesity and the metabolic syndrome. Excess fructose consumption can initiate or exacerbate NAFLD in...
6.
Walker J, Garcet S, Aleman J, Mason C, Danko D, Butler D, et al.
Sci Rep
. 2021 Apr;
11(1):7524.
PMID: 33790371
No abstract available.
7.
Walker J, Garcet S, Aleman J, Mason C, Danko D, Butler D, et al.
Sci Rep
. 2020 Aug;
10(1):14079.
PMID: 32826922
Obesity is accompanied by dysfunction of many organs, but effects on the skin have received little attention. We studied differences in epithelial thickness by histology and gene expression by Affymetrix...
8.
Munch N, Fang H, Ingermann J, Maurer H, Anand A, Kellner V, et al.
Gastroenterology
. 2019 Apr;
157(2):492-506.e2.
PMID: 30998992
Background & Aims: Barrett's esophagus (BE) is a precursor to esophageal adenocarcinoma (EAC). Progression from BE to cancer is associated with obesity, possibly due to increased abdominal pressure and gastroesophageal...
9.
Walker J, Eckardt P, Aleman J, Da Rosa J, Liang Y, Iizumi T, et al.
J Clin Transl Res
. 2019 Mar;
4(2):122-135.
PMID: 30873501
Background And Aim: The metabolic syndrome (MetS) is a pathological condition comprised of abdominal obesity, insulin resistance, hypertension, and hyperlipidemia. It has become a major threat globally, resulting in rapidly...
10.
Aleman J, Bokulich N, Swann J, Walker J, de Rosa J, Battaglia T, et al.
J Transl Med
. 2018 Sep;
16(1):244.
PMID: 30176893
Background: Microbiota and bile acids in the gastrointestinal tract profoundly alter systemic metabolic processes. In obese subjects, gradual weight loss ameliorates adipose tissue inflammation and related systemic changes. We assessed...