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Andrew J Dannenberg

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Articles 221
Citations 9100
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Recent Articles
1.
Zhang Y, Li Y, Peila R, Wang T, Xue X, Kaplan R, et al.
Am J Clin Nutr . 2024 Apr; 119(6):1514-1522. PMID: 38677521
Background: Interplay between lifestyle risk scores (LRSs) and genetic risk scores (GRSs) on obesity and related chronic diseases are underinvestigated and necessary for understanding obesity causes and developing prevention strategies....
2.
Cornelius P, Mayes B, Petersen J, Turnquist D, Dufour P, Dannenberg A, et al.
Mol Cancer Ther . 2024 Mar; 23(5):595-605. PMID: 38530115
Methionine aminopeptidase type 2 (METAP2) is a ubiquitous, evolutionarily conserved metalloprotease fundamental to protein biosynthesis which catalyzes removal of the N-terminal methionine residue from nascent polypeptides. METAP2 is an attractive...
3.
Weemering D, Midei M, Milner P, Gopalakrishnan V, Kumar A, Dannenberg A, et al.
Eur J Neurol . 2023 Aug; 30(12):3722-3731. PMID: 37550954
Background And Purpose: RT001 is a deuterated synthetic homologue of linoleic acid, which makes membrane polyunsaturated fatty acids resistant to lipid peroxidation, a process involved in motor neuron degeneration in...
4.
Peila R, Xue X, Qi Q, Dannenberg A, Allison M, Johnson K, et al.
J Am Heart Assoc . 2023 Jun; 12(12):e029111. PMID: 37306150
Background A lifestyle comprising a healthy diet, light alcohol consumption, no smoking, and moderate or intense physical activity has been associated with reduced risk of cardiovascular disease (CVD). We examined...
5.
Haczeyni F, Steensels S, Stein B, Jordan J, Li L, Dartigue V, et al.
bioRxiv . 2023 May; PMID: 37205525
One-sentence Summary: Thermogenic stress impairs mitochondrial energy utilization by forcing translocation of IM-bound proteins into the matrix.
6.
McDowell S, Milette S, Dore S, Yu M, Sorin M, Wilson L, et al.
J Exp Med . 2023 May; 220(8). PMID: 37166450
Obesity is characterized by chronic systemic inflammation and enhances cancer metastasis and mortality. Obesity promotes breast cancer metastasis to lung in a neutrophil-dependent manner; however, the upstream regulatory mechanisms of...
7.
Garcia M, Schadler K, Chandra J, Clinton S, Courneya K, Cruz-Monserrate Z, et al.
CA Cancer J Clin . 2023 Feb; 73(4):425-442. PMID: 36825928
Advances in energy balance and cancer research to date have largely occurred in siloed work in rodents or patients. However, substantial benefit can be derived from parallel studies in which...
8.
Ferrara C, Bai J, McNally E, Putzel G, Zhou X, Wang H, et al.
Cancer Prev Res (Phila) . 2022 Sep; 15(12):803-814. PMID: 36049217
Prevention Relevance: This study demonstrates novel mechanisms by which chemopreventive agents exert their effects and gut microbiota impact intestinal tumor development. These findings have the potential to lead to improved...
9.
Brown J, Sanidad K, Lucotti S, Lieber C, Cox R, Ananthanarayanan A, et al.
Gut Microbes . 2022 Aug; 14(1):2105609. PMID: 35915556
The gut microbiome is intricately coupled with immune regulation and metabolism, but its role in Coronavirus Disease 2019 (COVID-19) is not fully understood. Severe and fatal COVID-19 is characterized by...
10.
Chen I, Awasthi D, Hsu C, Song M, Chae C, Dannenberg A, et al.
J Immunol . 2022 Jun; 209(1):69-76. PMID: 35697385
Obesity is associated with increased cancer risk and weak responses to vaccination and sepsis treatment. Although dendritic cells (DCs) are fundamental for the initiation and maintenance of competent immune responses...