Peter O Fedichev
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Explore the profile of Peter O Fedichev including associated specialties, affiliations and a list of published articles.
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20
Citations
452
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Recent Articles
1.
Lyu Y, Fu Q, Wilczok D, Ying K, King A, Antebi A, et al.
Aging (Albany NY)
. 2024 Oct;
16(20):12955-12976.
PMID: 39418098
The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We,...
2.
Herzog C, Goeminne L, Poganik J, Barzilai N, Belsky D, Betts-LaCroix J, et al.
Nat Aging
. 2024 Sep;
4(10):1372-1383.
PMID: 39285015
Biomarkers of aging (BOA) are quantitative parameters that predict biological age and ideally its changes in response to interventions. In recent years, many promising molecular and omic BOA have emerged...
3.
Moqri M, Herzog C, Poganik J, Ying K, Justice J, Belsky D, et al.
Nat Med
. 2024 Feb;
30(2):360-372.
PMID: 38355974
The search for biomarkers that quantify biological aging (particularly 'omic'-based biomarkers) has intensified in recent years. Such biomarkers could predict aging-related outcomes and could serve as surrogate endpoints for the...
4.
Avchaciov K, Antoch M, Andrianova E, Tarkhov A, Menshikov L, Burmistrova O, et al.
Nat Commun
. 2022 Nov;
13(1):6529.
PMID: 36319638
Age is the leading risk factor for prevalent diseases and death. However, the relation between age-related physiological changes and lifespan is poorly understood. We combined analytical and machine learning tools...
5.
Ying K, Zhai R, Pyrkov T, Shindyapina A, Mariotti M, Fedichev P, et al.
Commun Med (Lond)
. 2022 May;
1:35.
PMID: 35602207
Background: Epidemiological studies revealed that the elderly and those with comorbidities are most affected by COVID-19, but it is important to investigate shared genetic mechanisms between COVID-19 risk and aging....
6.
Lopez-Fabuel I, Garcia-Macia M, Buondelmonte C, Burmistrova O, Bonora N, Alonso-Batan P, et al.
Nat Commun
. 2022 Jan;
13(1):536.
PMID: 35087090
CLN7 neuronal ceroid lipofuscinosis is an inherited lysosomal storage neurodegenerative disease highly prevalent in children. CLN7/MFSD8 gene encodes a lysosomal membrane glycoprotein, but the biochemical processes affected by CLN7-loss of...
7.
Ng T, Matchar D, Pyrkov T, Fedichev P, Chan A, Kennedy B
Aging (Albany NY)
. 2021 Aug;
13(16):20029-20049.
PMID: 34456185
Introduction: Despite associated with multiple geriatric disorders, whether housing type, an indicator of socioeconomic status (SES) and environmental factors, is associated with accelerated biological aging is unknown. Furthermore, although individuals...
8.
Pyrkov T, Avchaciov K, Tarkhov A, Menshikov L, Gudkov A, Fedichev P
Nat Commun
. 2021 May;
12(1):2765.
PMID: 34035236
We investigated the dynamic properties of the organism state fluctuations along individual aging trajectories in a large longitudinal database of CBC measurements from a consumer diagnostics laboratory. To simplify the...
9.
Pyrkov T, Sokolov I, Fedichev P
Aging (Albany NY)
. 2021 Mar;
13(6):7900-7913.
PMID: 33735108
Biological age acceleration (BAA) models based on blood tests or DNA methylation emerge as a standard for quantitative characterizations of the aging process. We demonstrate that deep neural networks trained...
10.
Santesmasses D, Castro J, Zenin A, Shindyapina A, Gerashchenko M, Zhang B, et al.
Aging Cell
. 2020 Oct;
19(10):e13230.
PMID: 33006233
COVID-19 is an ongoing pandemic caused by the SARS-CoV-2 coronavirus that poses one of the greatest challenges to public health in recent years. SARS-CoV-2 is known to preferentially target older...