Peter Cresswell
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Explore the profile of Peter Cresswell including associated specialties, affiliations and a list of published articles.
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130
Citations
6304
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Recent Articles
1.
Dolan B, Correa Gaviria T, Dong Y, Cresswell P, Dimopoulos G, Chuang Y, et al.
Nat Commun
. 2025 Jan;
16(1):592.
PMID: 39799117
Plasmodium, the causative agents of malaria, are obtained by mosquitoes from an infected human. Following Plasmodium acquisition by Anopheles gambiae, mosquito gamma-interferon-inducible lysosomal thiol reductase (mosGILT) plays a critical role...
2.
Sengupta D, Galicia-Pereyra R, Han P, Graham M, Liu X, Arshad N, et al.
J Immunol
. 2024 Feb;
212(7):1063-1068.
PMID: 38353614
Activation of naive CD8-positive T lymphocytes is mediated by dendritic cells that cross-present MHC class I (MHC-I)-associated peptides derived from exogenous Ags. The most accepted mechanism involves the translocation of...
3.
Arora G, Tang X, Cui Y, Yang J, Chuang Y, Joshi J, et al.
BMC Genomics
. 2024 Jan;
25(1):42.
PMID: 38191283
Gene-edited mosquitoes lacking a gamma-interferon-inducible lysosomal thiol reductase-like protein, namely (mosGILT) have lower Plasmodium infection, which is linked to impaired ovarian development and immune activation. The transcriptome of mosGILT Anopheles...
4.
Arora G, Tang X, Cui Y, Yang J, Chuang Y, Joshi J, et al.
bioRxiv
. 2023 Aug;
PMID: 37577703
Gene-edited mosquitoes lacking a g amma-interferon-inducible lysosomal thiol reductase-like protein, namely ( ) have lower infection, which is linked to impaired ovarian development and immune activation. The transcriptome of was...
5.
Chen X, Lu Q, Zhou H, Liu J, Nadorp B, Lasry A, et al.
Cell
. 2023 Aug;
186(18):3903-3920.e21.
PMID: 37557169
Immune-checkpoint blockade has revolutionized cancer treatment, but some cancers, such as acute myeloid leukemia (AML), do not respond or develop resistance. A potential mode of resistance is immune evasion of...
6.
Pawlak J, Hsu J, Xia H, Han P, Suh H, Grove T, et al.
PLoS Pathog
. 2023 Apr;
19(4):e1011286.
PMID: 37075076
Flaviviruses continue to emerge as global health threats. There are currently no Food and Drug Administration (FDA) approved antiviral treatments for flaviviral infections. Therefore, there is a pressing need to...
7.
Arshad N, Laurent-Rolle M, Ahmed W, Hsu J, Mitchell S, Pawlak J, et al.
Proc Natl Acad Sci U S A
. 2022 Dec;
120(1):e2208525120.
PMID: 36574644
Major histocompatibility complex class I (MHC-I) molecules, which are dimers of a glycosylated polymorphic transmembrane heavy chain and the small-protein β-microglobulin (βm), bind peptides in the endoplasmic reticulum that are...
8.
Jiang J, Taylor D, Kim E, Boyd L, Ahmad J, Mage M, et al.
Nat Commun
. 2022 Sep;
13(1):5470.
PMID: 36115831
Loading of MHC-I molecules with peptide by the catalytic chaperone tapasin in the peptide loading complex plays a critical role in antigen presentation and immune recognition. Mechanistic insight has been...
9.
Hsu J, Pawlak J, Laurent-Rolle M, Cresswell P
STAR Protoc
. 2022 Sep;
3(3):101654.
PMID: 36072758
Translational regulation is a fundamental step in gene expression with critical roles in biological processes within a cell. Here, we describe a protocol to assess translation activity in mammalian cells...
10.
Arshad N, Laurent-Rolle M, Ahmed W, Hsu J, Mitchell S, Pawlak J, et al.
bioRxiv
. 2022 May;
PMID: 35611331
Significance Statement: Viruses may down-regulate MHC class I expression on infected cells to avoid elimination by cytotoxic T cells. We report that the accessory proteins ORF7a and ORF3a of SARS-CoV-2...