Maudry Laurent-Rolle
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Explore the profile of Maudry Laurent-Rolle including associated specialties, affiliations and a list of published articles.
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25
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1893
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Recent Articles
1.
Interferon-Stimulated Genes and Immune Metabolites as Broad-Spectrum Biomarkers for Viral Infections
Huang C, Laurent-Rolle M, Grove T, Hsu J
Viruses
. 2025 Jan;
17(1).
PMID: 39861921
The type I interferon (IFN-I) response is a critical component of the immune defense against various viral pathogens, triggering the expression of hundreds of interferon-stimulated genes (ISGs). These ISGs encode...
2.
Boytz R, Laurent-Rolle M
PLoS Pathog
. 2024 Oct;
20(10):e1012626.
PMID: 39466723
Posttranslational modifications (PTMs) such as phosphorylation, ubiquitination, SUMOylation, and ISGylation are involved in various cellular pathways, including innate immunity and disease processes. Many viruses have developed sophisticated mechanisms to modulate...
3.
Boytz R, Keita K, Pawlak J, Laurent-Rolle M
Npj Viruses
. 2024 Oct;
2(1):47.
PMID: 39371935
Mitochondria are essential eukaryotic organelles that regulate a range of cellular processes, from metabolism to calcium homeostasis and programmed cell death. They serve as essential platforms for antiviral signaling proteins...
4.
Boytz R, Keita K, Pawlak J, Laurent-Rolle M
Viruses
. 2024 Feb;
16(2).
PMID: 38399982
The Eastern Equine Encephalitis Virus (EEEV) is an emerging public health threat, with the number of reported cases in the US increasing in recent years. EEEV is a BSL3 pathogen,...
5.
Pawlak J, Hsu J, Xia H, Han P, Suh H, Grove T, et al.
PLoS Pathog
. 2023 Apr;
19(4):e1011286.
PMID: 37075076
Flaviviruses continue to emerge as global health threats. There are currently no Food and Drug Administration (FDA) approved antiviral treatments for flaviviral infections. Therefore, there is a pressing need to...
6.
Arshad N, Laurent-Rolle M, Ahmed W, Hsu J, Mitchell S, Pawlak J, et al.
Proc Natl Acad Sci U S A
. 2022 Dec;
120(1):e2208525120.
PMID: 36574644
Major histocompatibility complex class I (MHC-I) molecules, which are dimers of a glycosylated polymorphic transmembrane heavy chain and the small-protein β-microglobulin (βm), bind peptides in the endoplasmic reticulum that are...
7.
Hsu J, Pawlak J, Laurent-Rolle M, Cresswell P
STAR Protoc
. 2022 Sep;
3(3):101654.
PMID: 36072758
Translational regulation is a fundamental step in gene expression with critical roles in biological processes within a cell. Here, we describe a protocol to assess translation activity in mammalian cells...
8.
Arshad N, Laurent-Rolle M, Ahmed W, Hsu J, Mitchell S, Pawlak J, et al.
bioRxiv
. 2022 May;
PMID: 35611331
Significance Statement: Viruses may down-regulate MHC class I expression on infected cells to avoid elimination by cytotoxic T cells. We report that the accessory proteins ORF7a and ORF3a of SARS-CoV-2...
9.
Hsu J, Laurent-Rolle M, Pawlak J, Xia H, Kunte A, Hee J, et al.
Mol Cell
. 2022 Mar;
82(9):1631-1642.e6.
PMID: 35316659
Innate immune responses induce hundreds of interferon-stimulated genes (ISGs). Viperin, a member of the radical S-adenosyl methionine (SAM) superfamily of enzymes, is the product of one such ISG that restricts...
10.
Morrison J, Laurent-Rolle M
Curr Res Virol Sci
. 2022 Jan;
3:100020.
PMID: 35072125
No abstract available.