Peter A Wark
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Explore the profile of Peter A Wark including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
1526
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0
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Recent Articles
1.
Liu G, Hsu A, Geirnaert S, Cong C, Nair P, Shen S, et al.
Mol Ther
. 2025 Jan;
33(3):917-932.
PMID: 39838644
Vitronectin (VTN) is an important extracellular matrix protein in tissue remodeling, but its role in chronic obstructive pulmonary disease (COPD) is unknown. We show that VTN regulates tissue remodeling through...
2.
Vanders R, Gomez H, Daly K, Wark P, Horvat J, Hansbro P
Am J Physiol Lung Cell Mol Physiol
. 2024 Sep;
327(6):L890-L904.
PMID: 39254092
Influenza A virus (IAV) infection is a major health risk during pregnancy. Although vaccination and antiviral agents are widely used and reduce IAV-induced symptoms, they are not sufficient to control...
3.
Liu G, Haw T, Starkey M, Philp A, Pavlidis S, Nalkurthi C, et al.
Nat Commun
. 2023 Nov;
14(1):7349.
PMID: 37963864
Toll-like receptor 7 (TLR7) is known for eliciting immunity against single-stranded RNA viruses, and is increased in both human and cigarette smoke (CS)-induced, experimental chronic obstructive pulmonary disease (COPD). Here...
4.
Faiz A, Mahbub R, Boedijono F, Tomassen M, Kooistra W, Timens W, et al.
Am J Respir Crit Care Med
. 2023 Sep;
208(10):1075-1087.
PMID: 37708400
IL-33 is a proinflammatory cytokine thought to play a role in the pathogenesis of asthma and chronic obstructive pulmonary disease (COPD). A recent clinical trial using an anti-IL-33 antibody showed...
5.
Salvato I, Ricciardi L, Dal Col J, Nigro A, Giurato G, Memoli D, et al.
Front Immunol
. 2023 Jul;
14:1192028.
PMID: 37483631
Introduction: The RNA-binding protein AU-rich-element factor-1 (AUF-1) participates to posttranscriptional regulation of genes involved in inflammation and cellular senescence, two pathogenic mechanisms of chronic obstructive pulmonary disease (COPD). Decreased AUF-1...
6.
Hough R, Wark P
Am J Respir Crit Care Med
. 2022 Sep;
207(5):503-504.
PMID: 36170639
No abstract available.
7.
Liu G, Jarnicki A, Paudel K, Lu W, Wadhwa R, Philp A, et al.
Eur Respir J
. 2022 Jul;
60(6).
PMID: 35777766
Background: COPD is the third leading cause of death worldwide. Cigarette smoke (CS)-induced chronic inflammation inducing airway remodelling, emphysema and impaired lung function is the primary cause. Effective therapies are...
8.
Johansen M, Mahbub R, Idrees S, Nguyen D, Miemczyk S, Pathinayake P, et al.
Am J Respir Crit Care Med
. 2022 May;
206(6):712-729.
PMID: 35549656
Patients with chronic obstructive pulmonary disease (COPD) develop more severe coronavirus disease (COVID-19); however, it is unclear whether they are more susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...
9.
Kim R, Sunkara K, Bracke K, Jarnicki A, Donovan C, Hsu A, et al.
Sci Transl Med
. 2021 Nov;
13(621):eaav7223.
PMID: 34818056
Chronic obstructive pulmonary disease (COPD) is the third leading cause of morbidity and death worldwide. Inhalation of cigarette smoke (CS) is the major cause in developed countries. Current therapies have...
10.
Lu Z, Van Eeckhoutte H, Liu G, Nair P, Jones B, Gillis C, et al.
Am J Respir Crit Care Med
. 2021 Jun;
204(6):667-681.
PMID: 34133911
Necroptosis, mediated by RIPK3 (receptor-interacting protein kinase 3) and MLKL (mixed lineage kinase domain-like), is a form of regulated necrosis that can drive tissue inflammation and destruction; however, its contribution...