Pete Clarner
Overview
Explore the profile of Pete Clarner including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
6
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0
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Recent Articles
1.
Hawley Z, Pardo I, Cao S, Zavodszky M, Casey F, Ferber K, et al.
Mol Ther
. 2024 Nov;
33(1):215-234.
PMID: 39563026
Dorsal root ganglion (DRG) toxicity has been consistently reported as a potential safety concern after delivery of adeno-associated viruses (AAVs) containing gene-replacement vectors but has yet to be reported for...
2.
Chen S, Hawley Z, Zavodszky M, Hana S, Ferretti D, Grubor B, et al.
Mol Ther Nucleic Acids
. 2023 Nov;
34:102057.
PMID: 37928442
Toxic gain-of-function mutations in superoxide dismutase 1 (SOD1) contribute to approximately 2%-3% of all amyotrophic lateral sclerosis (ALS) cases. Artificial microRNAs (amiRs) delivered by adeno-associated virus (AAV) have been proposed...
3.
Clarner P, Lau S, Chowdhury T, Guilmette E, Trapa P, Lo S, et al.
Mol Ther Methods Clin Dev
. 2021 Sep;
23:68-77.
PMID: 34589555
Robust assays to quantify adeno-associated virus (AAV) vector expression and potency are essential for gene therapy development. These assays inform the efficacy, safety, and pharmacodynamic profiles of AAV development candidates....
4.
Pu Y, Katz R, Chen Y, Kostrubsky V, Clarner P, Lo S, et al.
Hum Gene Ther
. 2021 Aug;
33(1-2):103-108.
PMID: 34376063
Adeno-associated viruses (AAVs) are nonenveloped viruses that have become popular gene transfer vectors to deliver DNA to target cells in clinical gene therapy. Iodixanol-based density gradient is one of the...