Payam Shahi
Overview
Explore the profile of Payam Shahi including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
625
Followers
0
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Recent Articles
1.
Jaffe D, Shahi P, Adams B, Chrisman A, Finnegan P, Raman N, et al.
Nature
. 2022 Oct;
611(7935):352-357.
PMID: 36289331
The vertebrate adaptive immune system modifies the genome of individual B cells to encode antibodies that bind particular antigens. In most mammals, antibodies are composed of heavy and light chains...
2.
Kim S, Clark I, Shahi P, Abate A
Anal Chem
. 2017 Dec;
90(2):1273-1279.
PMID: 29256243
Droplet microfluidics can identify and sort cells using digital reverse transcription polymerase chain reaction (RT-PCR) signals from individual cells. However, current methods require multiple microfabricated devices for enzymatic cell lysis...
3.
Karbaschi M, Shahi P, Abate A
Biomicrofluidics
. 2017 Aug;
11(4):044107.
PMID: 28794817
Droplet microfluidics can form and process millions of picoliter droplets with speed and ease, allowing the execution of huge numbers of biological reactions for high-throughput studies. However, at the conclusion...
4.
Cole R, Tang S, Siltanen C, Shahi P, Zhang J, Poust S, et al.
Proc Natl Acad Sci U S A
. 2017 Aug;
114(33):8728-8733.
PMID: 28760972
Although the elementary unit of biology is the cell, high-throughput methods for the microscale manipulation of cells and reagents are limited. The existing options either are slow, lack single-cell specificity,...
5.
Shahi P, Kim S, Haliburton J, Gartner Z, Abate A
Sci Rep
. 2017 Mar;
7:44447.
PMID: 28290550
Proteins are the primary effectors of cellular function, including cellular metabolism, structural dynamics, and information processing. However, quantitative characterization of proteins at the single-cell level is challenging due to the...
6.
Shahi P, Wang C, Lawson D, Slorach E, Lu A, Yu Y, et al.
Proc Natl Acad Sci U S A
. 2017 Mar;
114(12):3169-3174.
PMID: 28258171
The transcription factor GATA3 is the master regulator that drives mammary luminal epithelial cell differentiation and maintains mammary gland homeostasis. Loss of is associated with aggressive breast cancer development. We...
7.
Wang C, Shahi P, Huang J, Phan N, Sun Z, Lin Y, et al.
Mol Clin Oncol
. 2017 Jan;
6(1):7-18.
PMID: 28123722
The achaete-scute complex-like (ASCL) family, also referred to as 'achaete-scute complex homolog' or 'achaete-scute family basic helix-loop-helix transcription factor', is critical for proper development of the nervous system and deregulation...
8.
Shahi P, Slorach E, Wang C, Chou J, Lu A, Ruderisch A, et al.
J Biol Chem
. 2014 Dec;
290(6):3803-13.
PMID: 25538248
The NET (nocA, Nlz, elB, TLP-1) subfamily of zinc finger proteins is an important mediator during developmental processes. The evolutionary conserved zinc finger protein ZNF503/Zeppo2 (zinc finger elbow-related proline domain...
9.
Carstens J, Shahi P, Van Tsang S, Smith B, Creighton C, Zhang Y, et al.
Cancer Res
. 2013 Dec;
74(2):609-20.
PMID: 24305876
The reactive stroma surrounding tumor lesions performs critical roles ranging from supporting tumor cell proliferation to inducing tumorigenesis and metastasis. Therefore, it is critical to understand the cellular components and...
10.
Chou J, Shahi P, Werb Z
Cell Cycle
. 2013 Sep;
12(20):3262-71.
PMID: 24036551
The tumor microenvironment includes cells such as fibroblasts, immune cells, endothelial cells, as well as extracellular matrix (ECM), proteases, and cytokines. Together, these components participate in a complex crosstalk with...