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Michael M Ittmann

Explore the profile of Michael M Ittmann including associated specialties, affiliations and a list of published articles. Areas
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Articles 89
Citations 3653
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Recent Articles
1.
Charles C, Lloyd S, Piyarathna D, Gohlke J, Rasaily U, Putluri V, et al.
Am J Clin Exp Urol . 2023 Dec; 11(6):594-612. PMID: 38148936
Prostate cancer (PCa) is the second most common cancer and constitutes about 14.7% of total cancer cases. PCa is highly prevalent and more aggressive in African-American (AA) men than in...
2.
Pons-Faudoa F, Di Trani N, Capuani S, Facchi I, Wood A, Nehete B, et al.
J Control Release . 2023 Dec; 366:18-27. PMID: 38142963
Treatment nonadherence is a pressing issue in people living with HIV (PLWH), as they require lifelong therapy to maintain viral suppression. Poor adherence leads to antiretroviral (ARV) resistance, transmission to...
3.
Awad D, Cao P, Pulliam T, Spradlin M, Subramani E, Tellman T, et al.
Cancer Res . 2023 Dec; 84(5):703-724. PMID: 38038968
Significance: ATGL promotes prostate cancer metabolic plasticity and progression through both lipase-dependent and lipase-independent activity, informing strategies to target ATGL and lipid metabolism for cancer treatment.
4.
Krieger K, Mann E, Lee K, Bolterstein E, Jebakumar D, Ittmann M, et al.
DNA Repair (Amst) . 2023 Jun; 128:103529. PMID: 37390674
DNA adducts and strand breaks are induced by various exogenous and endogenous agents. Accumulation of DNA damage is implicated in many disease processes, including cancer, aging, and neurodegeneration. The continuous...
5.
Pons-Faudoa F, Di Trani N, Capuani S, Campa-Carranza J, Nehete B, Sharma S, et al.
Sci Transl Med . 2023 Jun; 15(702):eadg2887. PMID: 37379369
The impact of pre-exposure prophylaxis (PrEP) on slowing the global HIV epidemic hinges on effective drugs and delivery platforms. Oral drug regimens are the pillar of HIV PrEP, but variable...
6.
Pons-Faudoa F, Di Trani N, Capuani S, Hernandez N, Wood A, Nehete B, et al.
J Control Release . 2023 Apr; 358:116-127. PMID: 37120032
Several implantable long-acting (LA) delivery systems have been developed for sustained subcutaneous administration of tenofovir alafenamide (TAF), a potent and effective nucleotide reverse transcriptase inhibitor used for HIV pre-exposure prophylaxis...
7.
Kriseman M, Tang S, Liao Z, Jiang P, Parks S, Cope D, et al.
Commun Biol . 2023 Mar; 6(1):261. PMID: 36906706
The regenerative potential of the endometrium is attributed to endometrial stem cells; however, the signaling pathways controlling its regenerative potential remain obscure. In this study, genetic mouse models and endometrial...
8.
Villanueva H, Wells G, Miller M, Villanueva M, Pathak R, Castro P, et al.
Heliyon . 2023 Jan; 8(12):e12570. PMID: 36643309
Background: Non-metastatic muscle invasive urothelial bladder cancer (MIBC) has a poor prognosis and standard of care (SOC) includes neoadjuvant cisplatin-based chemotherapy (NAC) combined with cystectomy. Patients receiving NAC have at...
9.
Kumar V, Randhawa P, Bilodeau R, Mercola D, McClelland M, Agrawal A, et al.
Cancers (Basel) . 2022 Oct; 14(19). PMID: 36230846
The tumor microenvironment plays a crucial role in both the development and progression of prostate cancer. Furthermore, identifying protein and gene expression differences between different regions is valuable for treatment...
10.
Szwarc M, Hai L, Maurya V, Rajapakshe K, Perera D, Ittmann M, et al.
Cytokine . 2022 Sep; 160:156022. PMID: 36099756
Although conventional knockout and transgenic mouse models have significantly advanced our understanding of Receptor Activator of NF-κB Ligand (RANKL) signaling in intra-thymic crosstalk that establishes self-tolerance and later stages of...