Pavel V Baranov
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Explore the profile of Pavel V Baranov including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Loughran G, Andreev D, Terenin I, Namy O, Mikl M, Yordanova M, et al.
Nat Struct Mol Biol
. 2025 Mar;
PMID: 40033152
Dual reporters encoding two distinct proteins within the same mRNA have had a crucial role in identifying and characterizing unconventional mechanisms of eukaryotic translation. These mechanisms include initiation via internal...
2.
Wacholder A, Deutsch E, Kok L, van Dinter J, Lee J, Wright J, et al.
bioRxiv
. 2025 Mar;
PMID: 40027765
Thousands of short open reading frames (sORFs) are translated outside of annotated coding sequences. Recent studies have pioneered searching for sORF-encoded microproteins in mass spectrometry (MS)-based proteomics and peptidomics datasets....
3.
Han Z, Yan G, Jousma J, Nukala S, Amiri M, Kiniry S, et al.
J Clin Invest
. 2025 Feb;
135(3).
PMID: 39895626
Translational control shapes the proteome and is particularly important in regulating gene expression under stress. A key source of endothelial stress is treatment with tyrosine kinase inhibitors (TKIs), which lowers...
4.
Yordanova M, Slattery C, Baranova-Gurvich M, Engels M, Ting O, Swirski M, et al.
Res Sq
. 2025 Jan;
PMID: 39764142
Background: Nucleotide sequence can be translated in three reading frames from 5' to 3' producing distinct protein products. Many examples of RNA translation in two reading frames (dual coding) have...
5.
RiboSeq.Org: an integrated suite of resources for ribosome profiling data analysis and visualization
Tierney J, Swirski M, Tjeldnes H, Kiran A, Carancini G, Kiniry S, et al.
Nucleic Acids Res
. 2024 Nov;
53(D1):D268-D274.
PMID: 39540432
Ribosome profiling (Ribo-Seq) has revolutionised our understanding of translation, but the increasing complexity and volume of Ribo-Seq data present challenges for its reuse. Here, we formally introduce RiboSeq.Org, an integrated...
6.
Andreev D, Tierney J, Baranov P
J Mol Biol
. 2024 Nov;
436(23):168850.
PMID: 39486574
Upstream open reading frames (uORFs) are a class of translated regions (translons) in mRNA 5' leaders. uORFs are believed to be pervasive regulators of the translation of mammalian mRNAs. Some...
7.
Loughran G, De Pace R, Ding N, Zhang J, Jungreis I, Carancini G, et al.
bioRxiv
. 2024 Oct;
PMID: 39372779
Programmed ribosomal frameshifting is a process where a proportion of ribosomes change their reading frame on an mRNA, rephasing the ribosome relative to the mRNA. While frameshifting is commonly employed...
8.
Tierney J, Swirski M, Tjeldnes H, Mudge J, Kufel J, Whiffin N, et al.
Genome Res
. 2024 May;
34(4):530-538.
PMID: 38719470
The application of ribosome profiling has revealed an unexpected abundance of translation in addition to that responsible for the synthesis of previously annotated protein-coding regions. Multiple short sequences have been...
9.
OConnor P, Mahony J, Casey E, Baranov P, Van Sinderen D, Yordanova M
Microbiol Spectr
. 2024 Mar;
12(4):e0398923.
PMID: 38451091
Importance: The ribosome profiling technology has provided invaluable insights for understanding cellular translation and eukaryotic viral infections. However, its potential for investigating host-phage interactions remains largely untapped. Here, we applied...
10.
Fedorova A, Kiniry S, Andreev D, Mudge J, Baranov P
Nat Commun
. 2024 Jan;
15(1):228.
PMID: 38172129
No abstract available.