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Paul T Schumacker

Explore the profile of Paul T Schumacker including associated specialties, affiliations and a list of published articles. Areas
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Articles 137
Citations 10084
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Recent Articles
1.
Seam N, Chotirmall S, Martinez F, Halayko A, Harhay M, Davis S, et al.
Am J Respir Crit Care Med . 2024 Dec; PMID: 39680927
No abstract available.
2.
Stoolman J, Grant R, Poor T, Weinberg S, DAlessandro K, Tan J, et al.
Nat Metab . 2024 Jul; 6(8):1492-1504. PMID: 39048801
Microglia are necessary for central nervous system (CNS) function during development and play roles in ageing, Alzheimer's disease and the response to demyelinating injury. The mitochondrial respiratory chain (RC) is...
3.
Waypa G, Smith K, Mungai P, Dudley V, Helmin K, Singer B, et al.
J Clin Invest . 2024 May; 134(13). PMID: 38722697
Newborn mammalian cardiomyocytes quickly transition from a fetal to an adult phenotype that utilizes mitochondrial oxidative phosphorylation but loses mitotic capacity. We tested whether forced reversal of adult cardiomyocytes back...
4.
Mise K, Long J, Galvan D, Ye Z, Fan G, Sharma R, et al.
Nat Commun . 2024 Apr; 15(1):3022. PMID: 38589378
No abstract available.
5.
Mise K, Long J, Galvan D, Ye Z, Fan G, Sharma R, et al.
Nat Commun . 2024 Mar; 15(1):1965. PMID: 38438382
The mitochondrial electron transport chain (ETC) is a highly adaptive process to meet metabolic demands of the cell, and its dysregulation has been associated with diverse clinical pathologies. However, the...
6.
Schumacker P
Am J Respir Cell Mol Biol . 2023 Dec; 70(2):85-86. PMID: 38109692
No abstract available.
7.
Schumacker P
Am J Respir Cell Mol Biol . 2023 Sep; 69(6):601-602. PMID: 37769156
No abstract available.
8.
Mise K, Long J, Galvan D, Ye Z, Fan G, Serysheva I, et al.
Res Sq . 2023 Jul; PMID: 37461606
The mitochondrial electron transport chain (ETC) is a highly adaptive process to meet metabolic demands of the cell, and its dysregulation has been associated with diverse clinical pathologies. However, the...
9.
Sabharwal S, Dudley V, Landwerlin C, Schumacker P
J Biol Chem . 2023 Mar; 299(5):104624. PMID: 36935009
Cancer cells experience increased levels of oxidant stress as a consequence of oncogene activation, nucleotide biosynthesis, and growth factor receptor signaling. Mitochondria contribute to this redox stress by generating reactive...
10.
Zampese E, Wokosin D, Gonzalez-Rodriguez P, Guzman J, Tkatch T, Kondapalli J, et al.
Sci Adv . 2022 Sep; 8(39):eabp8701. PMID: 36179023
How do neurons match generation of adenosine triphosphate by mitochondria to the bioenergetic demands of regenerative activity? Although the subject of speculation, this coupling is still poorly understood, particularly in...