Paul M Wilkerson
Overview
Explore the profile of Paul M Wilkerson including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
529
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0
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Recent Articles
1.
Wilkerson P, Dedes K, Samartzis E, Dedes I, Lambros M, Natrajan R, et al.
Oncotarget
. 2016 Dec;
8(4):6057-6066.
PMID: 28002809
Purpose: To determine if models of ovarian clear cell carcinomas (OCCCs) harbouring defects in homologous recombination (HR) DNA repair of double strand breaks (DSBs) are sensitive to cisplatin and/or PARP...
2.
Ng C, Martelotto L, Gauthier A, Wen H, Piscuoglio S, Lim R, et al.
Genome Biol
. 2015 May;
16:107.
PMID: 25994018
Background: HER2 is overexpressed and amplified in approximately 15% of invasive breast cancers, and is the molecular target and predictive marker of response to anti-HER2 agents. In a subset of...
3.
Lopez-Knowles E, Wilkerson P, Ribas R, Anderson H, Mackay A, Ghazoui Z, et al.
Breast Cancer Res
. 2015 Apr;
17:35.
PMID: 25888249
Introduction: Aromatase inhibitors (AIs) are a vital component of estrogen receptor positive (ER+) breast cancer treatment. De novo and acquired resistance, however, is common. The aims of this study were...
4.
Piscuoglio S, Ng C, Martelotto L, Eberle C, Cowell C, Natrajan R, et al.
Mol Oncol
. 2014 Jul;
8(8):1588-602.
PMID: 25041824
Papillary carcinoma (PC) is a rare type of breast cancer, which comprises three histologic subtypes: encapsulated PC (EPC), solid PC (SPC) and invasive PC (IPC). Microarray-based gene expression and Affymetrix...
5.
Natrajan R, Wilkerson P, Marchio C, Piscuoglio S, Ng C, Wai P, et al.
J Pathol
. 2014 Jan;
232(5):553-65.
PMID: 24395524
Micropapillary carcinoma (MPC) is a rare histological special type of breast cancer, characterized by an aggressive clinical behaviour and a pattern of copy number aberrations (CNAs) distinct from that of...
6.
Wetterskog D, Wilkerson P, Rodrigues D, Lambros M, Fritchie K, Andersson M, et al.
Histopathology
. 2013 Feb;
62(4):543-50.
PMID: 23398044
Aims: The majority of adenoid cystic carcinomas (AdCCs), regardless of anatomical site, harbour the MYB-NFIB fusion gene. The aim of this study was to characterize the repertoire of somatic genetic...
7.
Wilkerson P, Reis-Filho J
Genes Chromosomes Cancer
. 2012 Dec;
52(4):333-55.
PMID: 23225572
Amplification at 11q13-q14 is a common event in cancers from multiple anatomical sites. This complex amplicon has multiple cores and several genes have been put forward as potential "drivers." In...
8.
Natrajan R, Mackay A, Wilkerson P, Lambros M, Wetterskog D, Arnedos M, et al.
Breast Cancer Res
. 2012 Mar;
14(2):R53.
PMID: 22433433
Introduction: The 19q12 locus is amplified in a subgroup of oestrogen receptor (ER)-negative grade III breast cancers. This amplicon comprises nine genes, including cyclin E1 (CCNE1), which has been proposed...
9.
Natrajan R, Mackay A, Lambros M, Weigelt B, Wilkerson P, Manie E, et al.
J Pathol
. 2012 Feb;
227(1):29-41.
PMID: 22362584
BRCA1 encodes a tumour suppressor protein that plays pivotal roles in homologous recombination (HR) DNA repair, cell-cycle checkpoints, and transcriptional regulation. BRCA1 germline mutations confer a high risk of early-onset...
10.
Hernandez L, Wilkerson P, Lambros M, Campion-Flora A, Nava Rodrigues D, Gauthier A, et al.
J Pathol
. 2012 Jan;
227(1):42-52.
PMID: 22252965
The mechanisms underlying the progression from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) of the breast are yet to be fully elucidated. Several hypotheses have been put...