Paul L Greenhaff
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Explore the profile of Paul L Greenhaff including associated specialties, affiliations and a list of published articles.
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118
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2841
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Recent Articles
11.
Shur N, Simpson E, Crossland H, Chivaka P, Constantin D, Cordon S, et al.
J Cachexia Sarcopenia Muscle
. 2022 Sep;
13(6):2999-3013.
PMID: 36058634
Background: Bed rest (BR) reduces whole-body insulin-stimulated glucose disposal (GD) and alters muscle fuel metabolism, but little is known about metabolic adaptation from acute to chronic BR nor the mechanisms...
12.
Crossland H, Brook M, Quinlan J, Franchi M, Phillips B, Wilkinson D, et al.
Geroscience
. 2022 Aug;
45(1):331-344.
PMID: 35948859
Exercise training can induce adaptive changes to tendon tissue both structurally and mechanically; however, the underlying compositional changes that contribute to these alterations remain uncertain in humans, particularly in the...
13.
Jaconelli M, Greenhaff P, Atherton P, Lobo D, Brook M
Clin Nutr
. 2022 Feb;
41(3):709-722.
PMID: 35168004
Background & Aims: Elective surgery induces skeletal muscle wasting driven by an imbalance between muscle protein synthesis and breakdown. From examination of diverse stable isotope tracer techniques, the dynamic processes...
14.
Alldritt I, Greenhaff P, Wilkinson D
Int J Mol Sci
. 2021 Dec;
22(24).
PMID: 34948370
Muscle deconditioning impairs both locomotor function and metabolic health, and is associated with reduced quality life and increased mortality rates. Despite an appreciation of the existence of phenomena such as...
15.
Chien H, Constantin D, Greenhaff P, Constantin-Teodosiu D
Biology (Basel)
. 2021 Nov;
10(11).
PMID: 34827089
The molecular mechanisms by which free fatty acids (FFA) inhibit muscle glucose oxidation is still elusive. We recently showed that C2C12 myotubes treated with palmitate (PAL) presented with greater protein...
16.
Latimer L, Constantin-Teodosiu D, Popat B, Constantin D, Houchen-Wolloff L, Bolton C, et al.
Eur Respir J
. 2021 Sep;
59(5).
PMID: 34588196
Background: Chronic obstructive pulmonary disease (COPD) patients exhibit lower peak oxygen uptake (' ), altered muscle metabolism and impaired exercise tolerance compared with age-matched controls. Whether these traits reflect muscle-level...
17.
Crossland H, Constantin-Teodosiu D, Greenhaff P
Int J Mol Sci
. 2021 Sep;
22(18).
PMID: 34575939
The peroxisome proliferator-activated receptor (PPAR) family of transcription factors has been demonstrated to play critical roles in regulating fuel selection, energy expenditure and inflammation in skeletal muscle and other tissues....
18.
McGing J, Radford S, Francis S, Serres S, Greenhaff P, Moran G
Aliment Pharmacol Ther
. 2021 Jul;
54(4):368-387.
PMID: 34228817
Background: Fatigue is the inability to achieve or maintain an expected work output resulting from central or peripheral mechanisms. The prevalence of inflammatory bowel disease (IBD) fatigue can reach 86%...
19.
Handzlik M, Tooth D, Constantin-Teodosiu D, Greenhaff P, Cole M
Biosci Rep
. 2021 May;
41(6).
PMID: 33973628
Carbohydrate metabolism in heart failure shares similarities to that following hypoxic exposure, and is thought to maintain energy homoeostasis in the face of reduced O2 availability. As part of these...
20.
Burns A, Nixon A, Mallinson J, Cordon S, Stephens F, Greenhaff P
J Physiol
. 2021 Feb;
599(8):2197-2210.
PMID: 33595094
Key Points: The trajectory, magnitude and localisation of metabolic perturbations caused by immobilisation (IMM) are unresolved. Forearm glucose uptake (FGU) in response to glucose feeding was determined in healthy men...