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Nathaniel J Szewczyk

Explore the profile of Nathaniel J Szewczyk including associated specialties, affiliations and a list of published articles. Areas
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Articles 90
Citations 2671
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Recent Articles
1.
Slade L, Etheridge T, Szewczyk N
Ageing Res Rev . 2024 Aug; 100:102456. PMID: 39153601
Understanding mechanisms of ageing remains a complex challenge for biogerontologists, but recent adaptations of evolutionary ageing theories offer a compelling lens in which to view both age-related molecular and physiological...
2.
Rutter L, MacKay M, Cope H, Szewczyk N, Kim J, Overbey E, et al.
Nat Commun . 2024 Jul; 15(1):6158. PMID: 39039045
Common and rare alleles are now being annotated across millions of human genomes, and omics technologies are increasingly being used to develop health and treatment recommendations. However, these alleles have...
3.
Cope H, Elsborg J, Demharter S, McDonald J, Wernecke C, Parthasarathy H, et al.
Commun Med (Lond) . 2024 Jun; 4(1):106. PMID: 38862781
Background: Spaceflight poses a unique set of challenges to humans and the hostile spaceflight environment can induce a wide range of increased health risks, including dermatological issues. The biology driving...
4.
Camera A, Tabetah M, Castaneda V, Kim J, Galsinh A, Haro-Vinueza A, et al.
Sci Rep . 2024 Jun; 14(1):13098. PMID: 38862573
Human space exploration poses inherent risks to astronauts' health, leading to molecular changes that can significantly impact their well-being. These alterations encompass genomic instability, mitochondrial dysfunction, increased inflammation, homeostatic dysregulation,...
5.
Rutter L, Cope H, MacKay M, Herranz R, Das S, Ponomarev S, et al.
Nat Commun . 2024 Jun; 15(1):4952. PMID: 38862505
Future multi-year crewed planetary missions will motivate advances in aerospace nutrition and telehealth. On Earth, the Human Cell Atlas project aims to spatially map all cell types in the human...
6.
Willis C, Calvaruso M, Angeloni D, Baatout S, Benchoua A, Bereiter-Hahn J, et al.
NPJ Microgravity . 2024 May; 10(1):50. PMID: 38693246
Periodically, the European Space Agency (ESA) updates scientific roadmaps in consultation with the scientific community. The ESA SciSpacE Science Community White Paper (SSCWP) 9, "Biology in Space and Analogue Environments",...
7.
Slade L, Deane C, Szewczyk N, Etheridge T, Whiteman M
Pharmacol Res . 2024 Apr; 203:107180. PMID: 38599468
Primary mitochondrial diseases (PMD) are amongst the most common inborn errors of metabolism causing fatal outcomes within the first decade of life. With marked heterogeneity in both inheritance patterns and...
8.
Cialdai F, Brown A, Baumann C, Angeloni D, Baatout S, Benchoua A, et al.
NPJ Microgravity . 2023 Oct; 9(1):84. PMID: 37865644
The present white paper concerns the indications and recommendations of the SciSpacE Science Community to make progress in filling the gaps of knowledge that prevent us from answering the question:...
9.
Baumann C, Deane C, Etheridge T, Szewczyk N, Willis C, Lowe D
J Appl Physiol (1985) . 2023 Oct; 135(5):1135-1145. PMID: 37823203
The ability of skeletal muscle to adapt to eccentric contractions has been suggested to be blunted in older muscle. If eccentric exercise is to be a safe and efficient training...
10.
Slade L, Bollen S, Bass J, Phillips B, Smith K, Wilkinson D, et al.
J Cachexia Sarcopenia Muscle . 2023 Sep; 14(6):2613-2622. PMID: 37722921
Background: Age-related muscle decline (sarcopenia) associates with numerous health risk factors and poor quality of life. Drugs that counter sarcopenia without harmful side effects are lacking, and repurposing existing pharmaceuticals...