Paul Franken
Overview
Explore the profile of Paul Franken including associated specialties, affiliations and a list of published articles.
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79
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3445
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Recent Articles
1.
Jan M, Jimenez S, Hor C, Dijk D, Skeldon A, Franken P
Cell Syst
. 2024 Jul;
15(7):610-627.e8.
PMID: 38986625
Analyses of gene-expression dynamics in research on circadian rhythms and sleep homeostasis often describe these two processes using separate models. Rhythmically expressed genes are, however, likely to be influenced by...
2.
Kompotis K, Mang G, Hubbard J, Jimenez S, Emmenegger Y, Polysopoulos C, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(3):e2220532121.
PMID: 38207077
MicroRNAs (miRNAs) are key post-transcriptional regulators of gene expression that have been implicated in a plethora of neuronal processes. Nevertheless, their role in regulating brain activity in the context of...
3.
Furrer M, Meier S, Jan M, Franken P, Sundset M, Brown S, et al.
Curr Biol
. 2023 Dec;
34(2):427-433.e5.
PMID: 38141616
Timing and quantity of sleep depend on a circadian (∼24-h) rhythm and a specific sleep requirement. Sleep curtailment results in a homeostatic rebound of more and deeper sleep, the latter...
4.
Franken P, Dijk D
Nat Rev Neurosci
. 2023 Dec;
25(1):43-59.
PMID: 38040815
Sleep is considered essential for the brain and body. A predominant concept is that sleep is regulated by circadian rhythmicity and sleep homeostasis, processes that were posited to be functionally...
5.
Luthi A, Franken P, Fulda S, Siclari F, van Someren E
Nat Neurosci
. 2023 Apr;
26(6):955-956.
PMID: 37081297
No abstract available.
6.
Gobet N, Jan M, Franken P, Xenarios I
PLoS Comput Biol
. 2022 Sep;
18(9):e1010552.
PMID: 36155976
Genetic variations affect behavior and cause disease but understanding how these variants drive complex traits is still an open question. A common approach is to link the genetic variants to...
7.
dukanovic N, La Spada F, Emmenegger Y, Niederhauser G, Preitner F, Franken P
Clocks Sleep
. 2022 Feb;
4(1):37-51.
PMID: 35225952
Both sleep-wake behavior and circadian rhythms are tightly coupled to energy metabolism and food intake. Altered feeding times in mice are known to entrain clock gene rhythms in the brain...
8.
Hoekstra M, Jan M, Katsioudi G, Emmenegger Y, Franken P
Elife
. 2021 Dec;
10.
PMID: 34895464
In the mouse, () expression in tissues peripheral to the suprachiasmatic nuclei (SCN) increases during sleep deprivation and at times of the day when animals are predominantly awake spontaneously, suggesting...
9.
Hubbard J, Kobayashi Frisk M, Ruppert E, Tsai J, Fuchs F, Robin-Choteau L, et al.
Proc Natl Acad Sci U S A
. 2021 Jun;
118(25).
PMID: 34155139
Artificial lighting, day-length changes, shift work, and transmeridian travel all lead to sleep-wake disturbances. The nychthemeral sleep-wake cycle (SWc) is known to be controlled by output from the central circadian...
10.
Sela Y, Hoekstra M, Franken P
Elife
. 2021 Mar;
10.
PMID: 33683202
Although brain temperature has neurobiological and clinical importance, it remains unclear which factors contribute to its daily dynamics and to what extent. Using a statistical approach, we previously demonstrated that...