Yann Emmenegger
Overview
Explore the profile of Yann Emmenegger including associated specialties, affiliations and a list of published articles.
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Citations
877
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Recent Articles
1.
Kompotis K, Mang G, Hubbard J, Jimenez S, Emmenegger Y, Polysopoulos C, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(3):e2220532121.
PMID: 38207077
MicroRNAs (miRNAs) are key post-transcriptional regulators of gene expression that have been implicated in a plethora of neuronal processes. Nevertheless, their role in regulating brain activity in the context of...
2.
dukanovic N, La Spada F, Emmenegger Y, Niederhauser G, Preitner F, Franken P
Clocks Sleep
. 2022 Feb;
4(1):37-51.
PMID: 35225952
Both sleep-wake behavior and circadian rhythms are tightly coupled to energy metabolism and food intake. Altered feeding times in mice are known to entrain clock gene rhythms in the brain...
3.
Hoekstra M, Jan M, Katsioudi G, Emmenegger Y, Franken P
Elife
. 2021 Dec;
10.
PMID: 34895464
In the mouse, () expression in tissues peripheral to the suprachiasmatic nuclei (SCN) increases during sleep deprivation and at times of the day when animals are predominantly awake spontaneously, suggesting...
4.
Sinturel F, Gos P, Petrenko V, Hagedorn C, Kreppel F, Storch K, et al.
Genes Dev
. 2021 Feb;
35(5-6):329-334.
PMID: 33602874
It has been assumed that the suprachiasmatic nucleus (SCN) synchronizes peripheral circadian oscillators. However, this has never been convincingly shown, since biochemical time series experiments are not feasible in behaviorally...
5.
Hubbard J, Gent T, Hoekstra M, Emmenegger Y, Mongrain V, Landolt H, et al.
Nat Commun
. 2020 Jun;
11(1):3130.
PMID: 32561733
Sleep-wake driven changes in non-rapid-eye-movement sleep (NREM) sleep (NREMS) EEG delta (δ-)power are widely used as proxy for a sleep homeostatic process. Here, we noted frequency increases in δ-waves in...
6.
Hor C, Yeung J, Jan M, Emmenegger Y, Hubbard J, Xenarios I, et al.
Proc Natl Acad Sci U S A
. 2019 Nov;
116(51):25773-25783.
PMID: 31776259
The timing and duration of sleep results from the interaction between a homeostatic sleep-wake-driven process and a periodic circadian process, and involves changes in gene regulation and expression. Unraveling the...
7.
Hoekstra M, Emmenegger Y, Hubbard J, Franken P
Elife
. 2019 Feb;
8.
PMID: 30720431
Sleep depriving mice affects clock-gene expression, suggesting that these contribute to sleep homeostasis. The mechanisms linking extended wakefulness to clock-gene expression are, however, not well understood. We propose CIRBP to...
8.
Kompotis K, Hubbard J, Emmenegger Y, Perrault A, Muhlethaler M, Schwartz S, et al.
Curr Biol
. 2019 Jan;
29(3):392-401.e4.
PMID: 30686738
Rocking has long been known to promote sleep in infants and, more recently, also in adults, increasing NREM sleep stage N2 and enhancing EEG slow waves and spindles. Nevertheless, whether...
9.
Diessler S, Jan M, Emmenegger Y, Guex N, Middleton B, Skene D, et al.
PLoS Biol
. 2018 Aug;
16(8):e2005750.
PMID: 30091978
Sleep is essential for optimal brain functioning and health, but the biological substrates through which sleep delivers these beneficial effects remain largely unknown. We used a systems genetics approach in...
10.
Mermet J, Yeung J, Hurni C, Mauvoisin D, Gustafson K, Jouffe C, et al.
Genes Dev
. 2018 Mar;
32(5-6):347-358.
PMID: 29572261
The circadian clock in animals orchestrates widespread oscillatory gene expression programs, which underlie 24-h rhythms in behavior and physiology. Several studies have shown the possible roles of transcription factors and...