Paul E Gray
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Explore the profile of Paul E Gray including associated specialties, affiliations and a list of published articles.
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35
Citations
481
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Recent Articles
21.
Keller B, Strohmeier V, Harder I, Unger S, Payne K, Andrieux G, et al.
Sci Immunol
. 2021 Oct;
6(64):eabh0891.
PMID: 34623902
Accumulation of human CD21 B cells in peripheral blood is a hallmark of chronic activation of the adaptive immune system in certain infections and autoimmune disorders. The molecular pathways underpinning...
22.
Russell A, Gray P, Ziegler J, Kim Y, Smith S, Sewell W, et al.
Proc Natl Acad Sci U S A
. 2021 Aug;
118(34).
PMID: 34417303
Sterile α motif domain-containing protein 9-like (SAMD9L) is encoded by a hallmark interferon-induced gene with a role in controlling virus replication that is not well understood. Here, we analyze SAMD9L...
23.
Pillay B, Fusaro M, Gray P, Statham A, Burnett L, Bezrodnik L, et al.
J Clin Invest
. 2020 Dec;
131(3).
PMID: 33290277
Inborn errors of immunity cause monogenic immune dysregulatory conditions such as severe and recurrent pathogen infection, inflammation, allergy, and malignancy. Somatic reversion refers to the spontaneous repair of a pathogenic...
24.
Williams P, Howard-Jones A, Hsu P, Palasanthiran P, Gray P, McMullan B, et al.
Pathology
. 2020 Sep;
52(7):801-808.
PMID: 32888706
As the SARS-CoV-2 pandemic unfolds across the globe, consistent themes are emerging with regard to aspects of SARS-CoV-2 infection and its associated disease entities in children. Overall, children appear to...
25.
Phan T, Gray P, Wong M, Macintosh R, Burnett L, Tangye S
J Clin Immunol
. 2020 Jun;
40(5):763-766.
PMID: 32483663
The Clinical Immunogenomics Research Consortium Australasia (CIRCA) crowdsources expertise in medicine, genomics, data science, and fundamental biology to diagnose and treat patients with rare inborn errors of immunity. This distributed...
26.
27.
Klinken E, Gray P, Pillay B, Worley L, Edwards E, Payne K, et al.
J Clin Immunol
. 2019 Dec;
40(2):299-309.
PMID: 31865525
Variants in MAGT1 have been identified as the cause of an immune deficiency termed X-linked immunodeficiency with magnesium defect, Epstein-Barr virus (EBV) infection and neoplasia (XMEN) disease. Here, we describe...
28.
Lau A, Avery D, Jackson K, Lenthall H, Volpi S, Brigden H, et al.
J Exp Med
. 2019 Dec;
217(2).
PMID: 31841125
Antibody-mediated autoimmune diseases are a major health burden. However, our understanding of how self-reactive B cells escape self-tolerance checkpoints to secrete pathogenic autoantibodies remains incomplete. Here, we demonstrate that patients...
29.
Gray P, McCarthy H, Siggs O, Saleem M, O Brien T, Frith K, et al.
Front Immunol
. 2019 Dec;
10:2659.
PMID: 31798588
Goodpasture's disease (GP) is mediated by autoantibodies that bind the glomerular and alveolar basement membrane, causing rapidly progressive glomerulonephritis with or without pulmonary hemorrhage. The autoantibodies bind neoepitopes formed upon...
30.
Zammit N, Siggs O, Gray P, Horikawa K, Langley D, Walters S, et al.
Nat Immunol
. 2019 Sep;
20(10):1299-1310.
PMID: 31534238
Resisting and tolerating microbes are alternative strategies to survive infection, but little is known about the evolutionary mechanisms controlling this balance. Here genomic analyses of anatomically modern humans, extinct Denisovan...