Patrick S Hume
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Explore the profile of Patrick S Hume including associated specialties, affiliations and a list of published articles.
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22
Citations
167
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Recent Articles
1.
Zheng J, Dhakal H, Qing E, Shrestha R, Geller A, Morrissey S, et al.
J Clin Invest
. 2025 Jan;
135(4).
PMID: 39773555
Neutrophils, particularly low-density neutrophils (LDNs), are believed to contribute to acute COVID-19 severity. Here, we showed that neutrophilia can be detected acutely and even months after SARS-CoV-2 infection in patients...
2.
Malcolm K, Ochoa A, Congel J, Hume P, Corley J, Wheeler E, et al.
Am J Respir Cell Mol Biol
. 2024 Nov;
PMID: 39589263
No abstract available.
3.
Chakraborty S, Cheng B, Edwards D, Gonzalez J, Chiu D, Zheng H, et al.
Immunity
. 2024 Nov;
58(1):182-196.e10.
PMID: 39541970
While most respiratory viral infections resolve with little harm to the host, severe symptoms arise when infection triggers an aberrant inflammatory response that damages lung tissue. Host regulators of virally...
4.
Hara N, Raclawska D, Morgan L, NeeDell J, Dao L, Kato A, et al.
Am J Respir Cell Mol Biol
. 2024 Oct;
PMID: 39447136
Mucus hypersecretion is an important pathological problem in respiratory diseases. Mucus accumulates in the airways of people with asthma, and it contributes to airflow limitation by forming plugs that occlude...
5.
Hynds R, Magin C, Ikonomou L, Aschner Y, Beers M, Burgess J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 May;
327(3):L327-L340.
PMID: 38772903
Repair and regeneration of a diseased lung using stem cells or bioengineered tissues is an exciting therapeutic approach for a variety of lung diseases and critical illnesses. Over the past...
6.
Blomberg R, Sompel K, Hauer C, Smith A, Pena B, Driscoll J, et al.
Adv Healthc Mater
. 2023 Nov;
13(4):e2302246.
PMID: 37953708
Lung cancer is the leading global cause of cancer-related deaths. Although smoking cessation is the best prevention, 50% of lung cancer diagnoses occur in people who have quit smoking. Research...
7.
Palmer W, Leaton L, Campos Codo A, Crute B, Roest J, Zhu S, et al.
Sci Immunol
. 2023 Jun;
8(84):eade5343.
PMID: 37390222
Most human killer cell immunoglobulin-like receptors (KIR) are expressed by natural killer (NK) cells and recognize HLA class I molecules as ligands. KIR3DL3 is a conserved but polymorphic inhibitory KIR...
8.
Petrache I, Pujadas E, Ganju A, Serban K, Borowiec A, Babbs B, et al.
JCI Insight
. 2023 May;
8(10).
PMID: 37212278
The pathogenesis of the marked pulmonary microvasculature injury, a distinguishing feature of COVID-19 acute respiratory distress syndrome (COVID-ARDS), remains unclear. Implicated in the pathophysiology of diverse diseases characterized by endothelial...
9.
Petrache I, Gupta A, Hume P, Rivera T, Schweitzer K, Chu H
Compr Physiol
. 2023 Mar;
13(2):4617-4630.
PMID: 36994770
EVALI is an acute inflammatory disease in response to lung cell injury induced by electronic cigarettes and vaping devices (EV) frequently containing Vitamin E Acetate or tetrahydrocannabinol additives, in the...
10.
Blomberg R, Sompel K, Hauer C, Pe A B, Driscoll J, Hume P, et al.
bioRxiv
. 2023 Mar;
PMID: 36993773
Lung cancer is the leading global cause of cancer-related deaths. Although smoking cessation is the best preventive action, nearly 50% of all lung cancer diagnoses occur in people who have...