Alexandra L McCubbrey
Overview
Explore the profile of Alexandra L McCubbrey including associated specialties, affiliations and a list of published articles.
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Citations
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Recent Articles
1.
King E, Zhao Y, Moore C, Steinhart B, Anderson K, Vestal B, et al.
JCI Insight
. 2024 Nov;
9(24).
PMID: 39509324
Macrophages are required for healthy repair of the lungs following injury, but they are also implicated in driving dysregulated repair with fibrosis. How these 2 distinct outcomes of lung injury...
2.
King E, McClendon J, Trinh T, Matsuda J, Lyn-Kew K, McCubbrey A, et al.
ERJ Open Res
. 2024 Oct;
10(5).
PMID: 39377087
https://bit.ly/3KgTJg1.
3.
McCubbrey A, Janssen W
Am J Respir Crit Care Med
. 2024 Jul;
210(4):385-387.
PMID: 39012242
No abstract available.
4.
Moore P, Anderson K, McManus S, Tu T, King E, Mould K, et al.
Am J Physiol Lung Cell Mol Physiol
. 2023 Feb;
324(4):L536-L549.
PMID: 36852927
Interstitial macrophages (IMs) reside in the lung tissue surrounding key structures including airways, vessels, and alveoli. Recent work has described IM heterogeneity during homeostasis, however, there are limited data on...
5.
Hume P, McClendon J, Kopf K, Harral J, Poczobutt J, McCubbrey A, et al.
Am J Physiol Lung Cell Mol Physiol
. 2022 Aug;
323(4):L391-L399.
PMID: 35943156
The pathogenesis of chronic obstructive pulmonary disease (COPD), a prevalent disease primarily caused by cigarette smoke exposure, is incompletely elucidated. Studies in humans and mice have suggested that hypoxia-inducible factor-1α...
6.
King E, Hume P, Janssen W, McCubbrey A
Methods Mol Biol
. 2022 Jun;
2506:257-267.
PMID: 35771477
Pulmonary macrophages are heterogeneous. Distinct populations of resident tissue macrophages exist in the lung airspace and tissue compartments during homeostasis. During inflammation, these are joined by monocyte-derived recruited macrophages. Flow...
7.
McCubbrey A, McManus S, McClendon J, Thomas S, Chatwin H, Reisz J, et al.
Cell Rep
. 2022 Jan;
38(2):110222.
PMID: 35021097
Phagocytosis of apoptotic cells, termed efferocytosis, is critical for tissue homeostasis and drives anti-inflammatory programming in engulfing macrophages. Here, we assess metabolites in naive and inflammatory macrophages following engulfment of...
8.
Poczobutt J, Mikosz A, Poirier C, Beatman E, Serban K, Gally F, et al.
Am J Respir Cell Mol Biol
. 2021 Mar;
64(5):629-640.
PMID: 33662226
Deficiency of ASM (acid sphingomyelinase) causes the lysosomal storage Niemann-Pick disease (NPD). Patients with NPD type B may develop progressive interstitial lung disease with frequent respiratory infections. Although several investigations...
9.
Evans C, McCubbrey A
Am J Respir Cell Mol Biol
. 2021 Mar;
64(5):523-524.
PMID: 33651669
No abstract available.
10.
Mould K, Moore C, McManus S, McCubbrey A, McClendon J, Griesmer C, et al.
Am J Respir Crit Care Med
. 2020 Oct;
203(8):946-956.
PMID: 33079572
Macrophages are the most abundant immune cell in the alveoli and small airways and are traditionally viewed as a homogeneous population during health. Whether distinct subsets of airspace macrophages are...