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Comprehensive Physiology

Comprehensive Physiology is a renowned scientific journal that publishes comprehensive and authoritative reviews on all aspects of physiology. Covering a wide range of topics, it provides in-depth analysis and synthesis of current research, making it an essential resource for researchers, educators, and students in the field of physiology.

Details
Abbr. Compr Physiol
Start 2011
End Continuing
Frequency Updated quarterly
e-ISSN 2040-4603
Country United States
Language English
Specialty Physiology
Metrics
h-index / Ranks: 2214 121
SJR / Ranks: 1671 1642
CiteScore / Ranks: 778 13.30
JIF / Ranks: 1190 5.8
Recent Articles
1.
Rosas P, Solaro R
Compr Physiol . 2025 Mar; 15(2):e70006. PMID: 40065530
This review focuses on p21-activated kinase 1 (Pak1), a multifunctional, highly conserved enzyme that regulates multiple downstream effectors present in many tissues. Upstream signaling via Ras-related small G-proteins, Cdc42/Rac1 promotes...
2.
Bhattacharyya A, Yadav P, Bhattacharya M
Compr Physiol . 2025 Feb; 15(1):e70004. PMID: 39980172
Idiopathic pulmonary fibrosis (IPF) is a chronic respiratory disease characterized by progressive scarring of the lung parenchyma. While two drugs have been approved by the US Food and Drug Administration...
3.
Singh A, Shadangi S, Gupta P, Rana S
Compr Physiol . 2025 Feb; 15(1):e70003. PMID: 39980164
Humans are perhaps evolutionarily engineered to get deeply addicted to sugar, as it not only provides energy but also helps in storing fats, which helps in survival during starvation. Additionally,...
4.
Fortnow L
Compr Physiol . 2025 Feb; 15(1):e70002. PMID: 39924710
Recent advances in our ability to collect and process information, particularly through artificial intelligence, opens up some exciting possibilities for understanding interorgan communication and treating conditions that arise from that...
5.
Yildiz R, Ganbold K, Sparman N, Rajbhandari P
Compr Physiol . 2025 Feb; 15(1):e70001. PMID: 39921241
Brown adipose tissue (BAT) and thermogenic beige fat within white adipose tissue (WAT), collectively known as adaptive thermogenic fat, dissipate energy as heat, offering promising therapeutic potential to combat obesity...
6.
Cairns M, Marais E, Joseph D, Essop M
Compr Physiol . 2025 Feb; 15(1):e70000. PMID: 39903543
Psychological stress has emerged as a critical risk factor for cardiovascular disease, especially in women. While female participation in clinical research has improved, sex-specific data analysis and reporting often remain...
7.
Krieger J, Daniels D, Lee S, Mastitskaya S, Langhans W
Compr Physiol . 2025 Jan; 15(1):e7. PMID: 39887844
Glucagon-like peptide-1 (GLP-1), a hormone released from enteroendocrine cells in the distal small and large intestines in response to nutrients and other stimuli, not only controls eating and insulin release,...
8.
Nichols T
Compr Physiol . 2024 Dec; 14(5):5789-5838. PMID: 39699088
The evolution of mechanisms for terrestrial locomotion has resulted in multi-segmented limbs that allow navigation on irregular terrains, changing of direction, manipulation of external objects, and control over the mechanical...
9.
Wang K, James A, Donovan G, Noble P
Compr Physiol . 2024 Dec; 14(5):5729-5762. PMID: 39699087
From the results of well-performed population health studies, we now have excellent data demonstrating that deficits in adult lung function may be present early in life, possibly as a result...
10.
Cornelius R, Maeoka Y, Shinde U, McCormick J
Compr Physiol . 2024 Dec; 14(5):5839-5874. PMID: 39699086
The rare disease Familial Hyperkalemic Hypertension (FHHt) is caused by mutations in the genes encoding Cullin 3 (CUL3), Kelch-Like 3 (KLHL3), and two members of the With-No-Lysine [K] (WNK) kinase...