Bradford J Smith
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Explore the profile of Bradford J Smith including associated specialties, affiliations and a list of published articles.
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63
Citations
657
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Recent Articles
1.
Neelakantan S, Myers K, Rizi R, Smith B, Avazmohammadi R
bioRxiv
. 2025 Mar;
PMID: 40027704
Lung biomechanics aims to understand the structure-function relationship in the lung under normal and pathological conditions. Pulmonary surfactant has a key structural role in lung function with a significant contribution...
2.
Grayck M, Smith B, Sosa A, Golden E, McCarthy W, Solar M, et al.
Am J Respir Cell Mol Biol
. 2025 Jan;
PMID: 39836061
Whether early life acetaminophen (APAP) exposures injure the developing lung is controversial. We sought to correlate murine pulmonary developmental expression profiles of to susceptibility to APAP exposure. P14 C57BL/6 mice...
3.
Wallbank A, Sosa A, Colson A, Farooqi H, Kaye E, Warner K, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Nov;
328(1):L159-L175.
PMID: 39601347
Mechanical ventilation (MV) is a necessary lifesaving intervention for patients with acute respiratory distress syndrome (ARDS) but it can cause ventilator-induced lung injury (VILI), which contributes to the high ARDS...
4.
Neelakantan S, Mukherjee T, Smith B, Myers K, Rizi R, Avazmohammadi R
Proc SPIE Int Soc Opt Eng
. 2024 Jul;
12928.
PMID: 39055486
Several lung diseases lead to alterations in regional lung mechanics, including ventilator- and radiation-induced lung injuries. Such alterations can lead to localized underventilation of the affected areas, resulting in the...
5.
Gottman D, Smith B
Front Netw Physiol
. 2024 May;
4:1392701.
PMID: 38757066
Introduction: Acute respiratory distress syndrome (ARDS) presents a significant clinical challenge, with ventilator-induced lung injury (VILI) being a critical complication arising from life-saving mechanical ventilation. Understanding the spatial and temporal...
6.
Perlman C, Knudsen L, Smith B
Am J Physiol Lung Cell Mol Physiol
. 2024 May;
327(2):L218-L231.
PMID: 38712433
Quantitative characterization of lung structures by morphometrical or stereological analysis of histological sections is a powerful means of elucidating pulmonary structure-function relations. The overwhelming majority of studies, however, fix lungs...
7.
Zimmermann R, Roeder F, Ruppert C, Smith B, Knudsen L
Am J Physiol Lung Cell Mol Physiol
. 2024 May;
327(1):L19-L39.
PMID: 38712429
Mechanical ventilation can cause ventilation-induced lung injury (VILI). The concept of stress concentrations suggests that surfactant dysfunction-induced microatelectases might impose injurious stresses on adjacent, open alveoli and function as germinal...
8.
Roeder F, Ropke T, Steinmetz L, Kolb M, Maus U, Smith B, et al.
Sci Rep
. 2024 Apr;
14(1):8080.
PMID: 38582767
Pre-injured lungs are prone to injury progression in response to mechanical ventilation. Heterogeneous ventilation due to (micro)atelectases imparts injurious strains on open alveoli (known as volutrauma). Hence, recruitment of (micro)atelectases...
9.
Agrawal D, Smith B, Sottile P, Hripcsak G, Albers D
Comput Biol Med
. 2024 Mar;
173:108349.
PMID: 38547660
Background: Ventilator dyssynchrony (VD) can worsen lung injury and is challenging to detect and quantify due to the complex variability in the dyssynchronous breaths. While machine learning (ML) approaches are...
10.
McGinn E, Mandell E, Smith B, Duke J, Bush A, Abman S
Am J Respir Crit Care Med
. 2024 Feb;
209(8):1041-1042.
PMID: 38301260
No abstract available.