Patrick OConnell
Overview
Explore the profile of Patrick OConnell including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
137
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0
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Recent Articles
1.
Sossamon J, OConnell P, Rastall D
Cerebellum
. 2025 Jan;
24(1):25.
PMID: 39753826
A 50-year-old woman with a 20-year history of gait instability presented with new-onset vertigo and oscillopsia. Examination revealed bilateral vestibular loss, cerebellar ataxia, sensory neuropathy, a "yes-yes" head tremor, nystagmus...
2.
Inyang K, Sim J, Clark K, Geron M, Monahan K, Evans C, et al.
Brain Behav Immun
. 2024 Sep;
123:399-410.
PMID: 39349285
Chronic pain often includes periods of transient amelioration and even remission that alternate with severe relapsing pain. While most research on chronic pain has focused on pain development and maintenance,...
3.
OConnell P, Stewart O, Bogunovic D
J Clin Immunol
. 2024 Aug;
44(8):186.
PMID: 39207514
No abstract available.
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Blake M, OConnell P, Aldhamen Y
Front Cell Dev Biol
. 2023 Jan;
10:1082195.
PMID: 36684449
In the setting of chronic antigen exposure in the tumor microenvironment (TME), cytotoxic CD8 T cells (CTLs) lose their immune surveillance capabilities and ability to clear tumor cells as a...
7.
OConnell P, Blake M, Godbehere S, Amalfitano A, Aldhamen Y
J Neuroinflammation
. 2022 Oct;
19(1):241.
PMID: 36199066
Background: Multiple sclerosis (MS) is a chronic, debilitating condition characterized by CNS autoimmunity stemming from a complex etiology involving both environmental and genetic factors. Our current understanding of MS points...
8.
Blake M, OConnell P, Pepelyayeva Y, Godbehere S, Aldhamen Y, Amalfitano A
BMC Immunol
. 2022 Mar;
23(1):9.
PMID: 35246034
Background: In addition to its role in antigen presentation, recent reports establish a new role for endoplasmic reticulum aminopeptidase 1 (ERAP1) in innate immunity; however, the mechanisms underlying these functions...
9.
OConnell P, Blake M, Pepelyayeva Y, Hyslop S, Godbehere S, Angarita A, et al.
Mol Ther Oncolytics
. 2022 Jan;
24:180-193.
PMID: 35036523
Targeted modulation of the immune system against tumors can achieve responses in otherwise refractory cancers, which has spurred efforts aimed at optimizing such strategies. To this end, we have previously...
10.
OConnell P, Blake M, Godbehere S, Aldhamen Y, Amalfitano A
J Immunol
. 2021 Nov;
207(12):2952-2965.
PMID: 34810226
Hundreds of genes have been linked to multiple sclerosis (MS); yet, the underlying mechanisms behind these associations have only been investigated in a fraction of cases. Endoplasmic reticulum aminopeptidase 1...