Of LAMA3 and LAMB3: A Novel Gene Therapy for Epidermolysis Bullosa
Overview
Overview
Journal
Mol Ther
Publisher
Cell Press
Specialties
Molecular Biology
Pharmacology
Pharmacology
Date
2024 Apr 17
PMID
38631349
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
References
1.
Lau C, Rouhani M, Maughan E, Orr J, Kolluri K, Pearce D
. Lentiviral expression of wild-type LAMA3A restores cell adhesion in airway basal cells from children with epidermolysis bullosa. Mol Ther. 2024; 32(5):1497-1509.
PMC: 11081864.
DOI: 10.1016/j.ymthe.2024.02.032.
View
2.
Kiritsi D, Has C, Bruckner-Tuderman L
. Laminin 332 in junctional epidermolysis bullosa. Cell Adh Migr. 2012; 7(1):135-41.
PMC: 3544777.
DOI: 10.4161/cam.22418.
View
3.
Pesch M, Konig S, Aumailley M
. Targeted Disruption of the Lama3 Gene in Adult Mice Is Sufficient to Induce Skin Inflammation and Fibrosis. J Invest Dermatol. 2016; 137(2):332-340.
DOI: 10.1016/j.jid.2016.07.040.
View
4.
McCarron A, Cmielewski P, Drysdale V, Parsons D, Donnelley M
. Effective viral-mediated lung gene therapy: is airway surface preparation necessary?. Gene Ther. 2022; 30(6):469-477.
PMC: 10284697.
DOI: 10.1038/s41434-022-00332-7.
View
5.
Fine J, Mellerio J
. Extracutaneous manifestations and complications of inherited epidermolysis bullosa: part I. Epithelial associated tissues. J Am Acad Dermatol. 2009; 61(3):367-84.
DOI: 10.1016/j.jaad.2009.03.052.
View