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David P W Rastall

Explore the profile of David P W Rastall including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 155
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Recent Articles
1.
Sossamon J, OConnell P, Rastall D
Cerebellum . 2025 Jan; 24(1):25. PMID: 39753826
A 50-year-old woman with a 20-year history of gait instability presented with new-onset vertigo and oscillopsia. Examination revealed bilateral vestibular loss, cerebellar ataxia, sensory neuropathy, a "yes-yes" head tremor, nystagmus...
2.
Pepelyayeva Y, Rastall D, Aldhamen Y, OConnell P, Raehtz S, Alyaqoub F, et al.
Sci Rep . 2018 Aug; 8(1):12464. PMID: 30127455
Ankylosing spondylitis (AS) is a prototypical sero-negative autoimmune disease that affects millions worldwide. Single nucleotide polymorphisms in the Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) gene have been linked to AS via...
3.
Green K, Rastall D, Eggenberger E
J Neuroophthalmol . 2018 Apr; 38(3):347-349. PMID: 29608536
A 62-year-old woman developed a right horizontal gaze palsy and ipsilateral facial nerve palsy due to a right pontine tegmentum infarct. This constitutes a forme fruste of the eight-and-a-half syndrome...
4.
Rastall D, Amalfitano A
Curr Treat Options Neurol . 2017 Nov; 19(12):45. PMID: 29101575
Purpose of review Lysosomal storage disorders (LSDs) are a class of genetic disorders that are a testing ground for the invention of novel therapeutics including enzyme replacement therapy (ERT), substrate...
5.
Rastall D, Alyaquob F, OConnell P, Pepelyayeva Y, Peters D, Godbehere-Roosa S, et al.
Int Immunol . 2017 Aug; 29(6):277-289. PMID: 28814066
Specific variants of endoplasmic reticulum-associated aminopeptidase 1 (ERAP1) identified by genome-wide association study modify the risk for developing ankylosing spondylitis. We previously confirmed that disease-associated ERAP1 variants have altered enzymatic...
6.
Aldhamen Y, Rastall D, Chen W, Seregin S, Pereira-Hicks C, Godbehere S, et al.
Vaccine . 2016 May; 34(27):3109-3118. PMID: 27151882
The CD2-like receptor activating cytotoxic cell (CRACC) receptor is a member of the SLAM family of receptors that are found on several types of immune cells. We previously demonstrated that...
7.
Aldhamen Y, Pepelyayeva Y, Rastall D, Seregin S, Zervoudi E, Koumantou D, et al.
J Innate Immun . 2015 Jan; 7(3):275-89. PMID: 25591727
Endoplasmic reticulum aminopeptidase 1 (ERAP1) gene polymorphisms have been linked to several autoimmune diseases; however, the molecular mechanisms underlying these associations are not well understood. Recently, we demonstrated that ERAP1...
8.
Koestler B, Seregin S, Rastall D, Aldhamen Y, Godbehere S, Amalfitano A, et al.
Clin Vaccine Immunol . 2014 Sep; 21(11):1550-9. PMID: 25230938
The bacterial second messenger cyclic di-GMP (c-di-GMP) stimulates inflammation by initiating innate immune cell recruitment and triggering the release of proinflammatory cytokines and chemokines. These properties make c-di-GMP a promising...
9.
Rastall D, Aldhamen Y, Seregin S, Godbehere S, Amalfitano A
Int Immunol . 2014 Aug; 26(12):685-95. PMID: 25087231
Endoplasmic reticulum aminopeptidase 1 (ERAP1) is a critical component of the adaptive immune system that has been shown to increase or decrease the presentation of specific peptides on MHC class...
10.
Seregin S, Rastall D, Evnouchidou I, Aylsworth C, Quiroga D, Kamal R, et al.
Autoimmunity . 2013 Sep; 46(8):497-508. PMID: 24028501
Ankylosing spondylitis (AS) is a chronic systemic arthritic disease that leads to significant disability and loss of quality of life in the ∼0.5% of the worldwide human population it affects....