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Patricia M Washington

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Articles 12
Citations 526
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Recent Articles
1.
Washington P, Lee C, Dwyer M, Konofagou E, Kernie S, Morrison 3rd B
J Cereb Blood Flow Metab . 2019 Oct; 40(10):2026-2037. PMID: 31648593
Cerebral edema and the subsequent increased intracranial pressure are associated with mortality and poor outcome following traumatic brain injury. Previous in vitro studies have shown that the Gibbs-Donnan effect, which...
2.
Main B, Villapol S, Sloley S, Barton D, Parsadanian M, Agbaegbu C, et al.
Mol Neurodegener . 2018 Apr; 13(1):17. PMID: 29618365
Background: Traumatic Brain Injury (TBI) is a major cause of disability and mortality, to which there is currently no comprehensive treatment. Blood Brain Barrier (BBB) dysfunction is well documented in...
3.
Washington P, Burns M
J Neuropathol Exp Neurol . 2016 Jun; 75(8):770-778. PMID: 27297672
The apolipoprotein E (apoE) protein is involved in clearance of β-amyloid (Aβ) from the brain; and the APOE4 gene is associated with Aβ plaque formation in humans following traumatic brain...
4.
Washington P, Villapol S, Burns M
Exp Neurol . 2015 Jun; 275 Pt 3:381-388. PMID: 26091850
Neuropathological studies of human traumatic brain injury (TBI) cases have described amyloid plaques acutely after a single severe TBI, and tau pathology after repeat mild TBI (mTBI). This has helped...
5.
Hong S, Washington P, Kim A, Yang C, Yu T, Kernie S
J Neurotrauma . 2015 Apr; 33(4):362-74. PMID: 25905575
Partial recovery from even severe traumatic brain injury (TBI) is ubiquitous and occurs largely through unknown mechanisms. Recent evidence suggests that hippocampal neural stem/progenitor cell (NSPC) activation and subsequent neurogenesis...
6.
Yu T, Washington P, Kernie S
Neuroscientist . 2014 Dec; 22(1):61-71. PMID: 25520428
Partial recovery from brain injury due to trauma, hypoxia, or stroke, is ubiquitous and occurs largely through unknown mechanisms. It is now well accepted that injury enhances proliferation of quiescent...
7.
Washington P, Morffy N, Parsadanian M, Zapple D, Burns M
J Neurotrauma . 2013 Sep; 31(1):125-34. PMID: 24050316
Soluble amyloid-beta (Aβ) oligomers are hypothesized to be the pathogenic species in Alzheimer's disease (AD), and increased levels of oligomers in the brain subsequent to traumatic brain injury (TBI) may...
8.
Dumanis S, Ullrich L, Washington P, Forcelli P
CBE Life Sci Educ . 2013 Sep; 12(3):419-28. PMID: 24006391
Grantsmanship is an integral component of surviving and thriving in academic science, especially in the current funding climate. Therefore, any additional opportunities to write, read, and review grants during graduate...
9.
Winston C, Chellappa D, Wilkins T, Barton D, Washington P, Loane D, et al.
J Neurotrauma . 2013 Jul; 30(23):1966-72. PMID: 23879560
The clinical manifestations that occur after traumatic brain injury (TBI) include a wide range of cognitive, emotional, and behavioral deficits. The loss of excitatory synapses could potentially explain why such...
10.
Washington P, Forcelli P, Wilkins T, Zapple D, Parsadanian M, Burns M
J Neurotrauma . 2012 May; 29(13):2283-96. PMID: 22642287
Traumatic brain injury (TBI) can cause a broad array of behavioral problems including cognitive and emotional deficits. Human studies comparing neurobehavioral outcomes after TBI suggest that cognitive impairments increase with...