Parameswaran Ramakrishnan
Overview
Explore the profile of Parameswaran Ramakrishnan including associated specialties, affiliations and a list of published articles.
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36
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1225
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Recent Articles
1.
Liu A, Sarkar N, Cress J, de Jesus T, Vadlakonda A, Centore J, et al.
EBioMedicine
. 2024 Nov;
110:105452.
PMID: 39586195
Background: Nuclear factor kappa B (NF-κB) c-Rel is a psoriasis susceptibility locus, however mechanisms underlying c-Rel transactivation during disease are poorly understood. Inflammation in psoriasis can be triggered following Toll-like...
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Ramakrishnan P
J Biol Chem
. 2024 May;
300(6):107349.
PMID: 38718861
The dynamic and reversible modification of nuclear and cytoplasmic proteins by O-GlcNAcylation significantly impacts the function and dysfunction of the immune system. O-GlcNAcylation plays crucial roles under both physiological and...
5.
Schauner R, Cress J, Hong C, Wald D, Ramakrishnan P
Front Immunol
. 2024 Apr;
15:1327405.
PMID: 38601153
Introduction: Acute myeloid leukemia (AML) is the most common acute leukemia in adults with an overall poor prognosis and high relapse rate. Multiple factors including genetic abnormalities, differentiation defects and...
6.
Gowd V, Kass J, Sarkar N, Ramakrishnan P
Cell Mol Life Sci
. 2024 Feb;
81(1):89.
PMID: 38351330
Sam68 is a ubiquitously expressed KH-domain containing RNA-binding protein highly studied for its involvement in regulating multiple steps of RNA metabolism. Sam68 also contains multiple protein-protein interaction regions such as...
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Liu A, Basavarajappa S, Sarkar N, Bruchez A, Ramakrishnan P
STAR Protoc
. 2023 Feb;
4(1):102127.
PMID: 36853707
Here, we provide a protocol for the design, expression, purification, and functional studies of an engineered trimeric version of the receptor-binding domain (tRBD) of SARS-CoV-2 spike protein. We describe the...
8.
Basavarajappa S, Liu A, Bruchez A, Li Z, Suzart V, Liu Z, et al.
iScience
. 2022 Jul;
25(8):104716.
PMID: 35813876
The COVID-19 pandemic has caused over four million deaths and effective methods to control CoV-2 infection, in addition to vaccines, are needed. The CoV-2 binds to the ACE2 on human...
9.
Feinberg D, Ramakrishnan P, Wong D, Asthana A, Parameswaran R
Front Immunol
. 2022 Apr;
13:841299.
PMID: 35479087
Natural killer (NK) cells mediate killing of malignant and virus-infected cells, a property that is explored as a cell therapy approach in the clinic. Various cell intrinsic and extrinsic factors...
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Zhang L, Ghosh S, Basavarajappa S, Chen Y, Shrestha P, Penfield J, et al.
iScience
. 2022 Feb;
25(3):103856.
PMID: 35128350
New approaches to complement vaccination are needed to combat the spread of SARS-CoV-2 and stop COVID-19-related deaths and medical complications. Human beta defensin 2 (hBD-2) is a naturally occurring epithelial...