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Reshmi Parameswaran

Explore the profile of Reshmi Parameswaran including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 368
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Recent Articles
1.
Uppin V, Gibbons H, Troje M, Feinberg D, Webber B, Moriarity B, et al.
J Autoimmun . 2025 Jan; 151:103369. PMID: 39832454
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by dysregulated B cell activation, autoantibody production, and nephritis. B cell activating factor (BAFF) overexpression enhances autoreactive B-cell survival, driving autoimmunity....
2.
Fritz C, Wong D, Rock P, Burack R, Radhakrishnan A, Parameswaran R
Oncoimmunology . 2024 Nov; 13(1):2432062. PMID: 39604816
Hairy cell leukemia variant (HCL-v) is a rare malignancy of clonal mature B-cells that follows a chronic disease course. HCL-v patients are often resistant to purine nucleoside analogs, which are...
3.
Wong D, Fritz C, Feinberg D, Huang A, Parameswaran R
Cancer Res Commun . 2023 Jun; 3(5):793-806. PMID: 37377891
Significance: This study reports a role for p35 in NK-cell cytotoxicity and this might help to improve NK-cell adoptive therapy.
4.
Feinberg D, Ramakrishnan P, Wong D, Asthana A, Parameswaran R
Front Immunol . 2022 Apr; 13:841299. PMID: 35479087
Natural killer (NK) cells mediate killing of malignant and virus-infected cells, a property that is explored as a cell therapy approach in the clinic. Various cell intrinsic and extrinsic factors...
5.
Wong D, Roy N, Zhang K, Anukanth A, Asthana A, Shirkey-Son N, et al.
Nat Commun . 2022 Jan; 13(1):217. PMID: 35017485
B cell-activating factor (BAFF) binds the three receptors BAFF-R, BCMA, and TACI, predominantly expressed on mature B cells. Almost all B cell cancers are reported to express at least one...
6.
Vicioso Y, Wong D, Roy N, Das N, Zhang K, Ramakrishnan P, et al.
Front Immunol . 2021 May; 12:652786. PMID: 33995369
Natural Killer (NK) cells are cytotoxic lymphocytes critical to the innate immune system. We found that germline deficiency of NF-κB c-Rel results in a marked decrease in cytotoxic function of...
7.
Zhang K, Roy N, Vicioso Y, Woo J, Beck R, de Lima M, et al.
Oncoimmunology . 2021 Mar; 10(1):1893501. PMID: 33747637
Mantle cell lymphoma (MCL) is an aggressive form of B cell non-Hodgkin's lymphoma and remains incurable under current treatment modalities. One of the main reasons for treatment failure is the...
8.
Vicioso Y, Gram H, Beck R, Asthana A, Zhang K, Wong D, et al.
Cancer Immunol Res . 2019 May; 7(7):1106-1119. PMID: 31138521
Drug-resistant acute lymphoblastic leukemia (ALL) patients do not respond to standard chemotherapy, and an urgent need exists to develop new treatment strategies. Our study exploited the presence of B-cell activating...
9.
Ryva B, Zhang K, Asthana A, Wong D, Vicioso Y, Parameswaran R
Front Oncol . 2019 Mar; 9:100. PMID: 30847305
Dietary lectins are carbohydrate-binding proteins found in food sources. We used a panel of seven dietary lectins to analyze cytotoxicity against hematological cancers. Wheat germ agglutinin (WGA), even at low...
10.
Asthana A, Ramakrishnan P, Vicioso Y, Zhang K, Parameswaran R
Mol Cancer Ther . 2018 Aug; 17(10):2226-2237. PMID: 30082471
Treatment for acute myeloid leukemia (AML) has remained unchanged for past 40 years. Targeting cell metabolism is a promising avenue for future cancer therapy. We found that enzymes involved in...