Par Nordlund
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Explore the profile of Par Nordlund including associated specialties, affiliations and a list of published articles.
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136
Citations
6332
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Recent Articles
1.
Zhao S, Zhang X, Zhao Z, Qian P, Liu W, Zeng Z, et al.
Annu Int Conf IEEE Eng Med Biol Soc
. 2025 Mar;
2024:1-4.
PMID: 40039529
Considering the significant role of protein function probes in medicine development and health monitoring, we design a hybrid model based on traditional and deep learning methods to predict protein functions...
2.
Ramos A, Liang Y, Surova O, Bacanu S, Gerault M, Mandal T, et al.
Cell Rep
. 2024 Oct;
43(10):114784.
PMID: 39365699
Cellular phenotypes of apoptosis, as well as the activation of apoptosis caspase cascades, are well described. However, sequences and locations of early biochemical effector events after apoptosis initiation are still...
3.
Wirjanata G, Lin J, Dziekan J, El Sahili A, Chung Z, Tjia S, et al.
Cell Chem Biol
. 2024 Apr;
31(4):743-759.e8.
PMID: 38593807
Identification of new druggable protein targets remains the key challenge in the current antimalarial development efforts. Here we used mass-spectrometry-based cellular thermal shift assay (MS-CETSA) to identify potential targets of...
4.
Gerault M, Granjeaud S, Camoin L, Nordlund P, Dai L
Brief Bioinform
. 2024 Apr;
25(3).
PMID: 38557673
IMPRINTS-CETSA (Integrated Modulation of Protein Interaction States-Cellular Thermal Shift Assay) provides a highly resolved means to systematically study the interactions of proteins with other cellular components, including metabolites, nucleic acids...
5.
Zhao S, Yang X, Zeng Z, Qian P, Zhao Z, Dai L, et al.
Sci Rep
. 2024 Jan;
14(1):1878.
PMID: 38253642
Mass spectrometry-coupled cellular thermal shift assay (MS-CETSA), a biophysical principle-based technique that measures the thermal stability of proteins at the proteome level inside the cell, has contributed significantly to the...
6.
Yang F, Jia L, Zhou H, Huang J, Hou M, Liu F, et al.
Acta Pharmacol Sin
. 2023 Oct;
45(2):391-404.
PMID: 37803139
Hepatocellular carcinoma (HCC) is one of the most common and deadly cancers in the world. The therapeutic outlook for HCC patients has significantly improved with the advent and development of...
7.
Zeng Z, Zhao S, Da Q, Qian P, Leong T, Dai L, et al.
Annu Int Conf IEEE Eng Med Biol Soc
. 2022 Sep;
2022:1647-1650.
PMID: 36085941
Cellular Thermal Shift Assay (CETSA) has been widely used in drug discovery, cancer cell biology, immunology, etc. One of the barriers for CETSA applications is that CETSA experiments have to...
8.
Yang X, Da Q, Qian P, Veeravalli B, Leong T, Dai L, et al.
Annu Int Conf IEEE Eng Med Biol Soc
. 2022 Sep;
2022:1659-1662.
PMID: 36085889
The Cellular Thermal Shift Assay (CETSA) is a biophysical assay based on the principle of ligand-induced thermal stabilization of target proteins. This technology has revolutionized cell-based target engagement studies and...
9.
Frosi Y, Lin Y, Shimin J, Ramlan S, Hew K, Engman A, et al.
Nat Commun
. 2022 Aug;
13(1):4854.
PMID: 35982046
An attractive approach to target intracellular macromolecular interfaces and to model putative drug interactions is to design small high-affinity proteins. Variable domains of the immunoglobulin heavy chain (VH domains) are...
10.
Ceder S, Eriksson S, Liang Y, Cheteh E, Zhang S, Fujihara K, et al.
Cell Death Dis
. 2022 Aug;
13(8):672.
PMID: 35922423
No abstract available.