Panayiota Poirazi
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Explore the profile of Panayiota Poirazi including associated specialties, affiliations and a list of published articles.
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88
Citations
2623
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Recent Articles
31.
Park J, Papoutsi A, Ash R, Marin M, Poirazi P, Smirnakis S
Nat Commun
. 2019 Nov;
10(1):5372.
PMID: 31772192
Pyramidal neurons integrate synaptic inputs from basal and apical dendrites to generate stimulus-specific responses. It has been proposed that feed-forward inputs to basal dendrites drive a neuron's stimulus preference, while...
32.
Richards B, Lillicrap T, Beaudoin P, Bengio Y, Bogacz R, Christensen A, et al.
Nat Neurosci
. 2019 Oct;
22(11):1761-1770.
PMID: 31659335
Systems neuroscience seeks explanations for how the brain implements a wide variety of perceptual, cognitive and motor tasks. Conversely, artificial intelligence attempts to design computational systems based on the tasks...
33.
Tzilivaki A, Kastellakis G, Poirazi P
Nat Commun
. 2019 Aug;
10(1):3664.
PMID: 31413258
Interneurons are critical for the proper functioning of neural circuits. While often morphologically complex, their dendrites have been ignored for decades, treating them as linear point neurons. Exciting new findings...
34.
Ebner C, Ledderose J, Zolnik T, Dominiak S, Turko P, Papoutsi A, et al.
Front Synaptic Neurosci
. 2019 Jun;
11:16.
PMID: 31178713
The advent of optogenetic methods has made it possible to use endogeneously produced molecules to image and manipulate cellular, subcellular, and synaptic activity. It has also led to the development...
35.
Turi G, Li W, Chavlis S, Pandi I, OHare J, Priestley J, et al.
Neuron
. 2019 Feb;
101(6):1150-1165.e8.
PMID: 30713030
Diverse computations in the neocortex are aided by specialized GABAergic interneurons (INs), which selectively target other INs. However, much less is known about how these canonical disinhibitory circuit motifs contribute...
36.
Ait Ouares K, Filipis L, Tzilivaki A, Poirazi P, Canepari M
J Neurosci
. 2019 Jan;
39(11):1969-1981.
PMID: 30630881
In cerebellar Purkinje neuron dendrites, the transient depolarization associated with a climbing fiber (CF) EPSP activates voltage-gated Ca channels (VGCCs), voltage-gated K channels (VGKCs), and Ca-activated SK and BK K...
37.
Frank A, Huang S, Zhou M, Gdalyahu A, Kastellakis G, Silva T, et al.
Nat Commun
. 2018 Jan;
9(1):422.
PMID: 29379017
Modeling studies suggest that clustered structural plasticity of dendritic spines is an efficient mechanism of information storage in cortical circuits. However, why new clustered spines occur in specific locations and...
38.
Poirazi P, Kastellakis G
Neuron
. 2017 Sep;
96(1):9-10.
PMID: 28957680
In this issue of Neuron, Costa et al. (2017) introduce a theoretical framework that predicts the ratio of presynaptic and postsynaptic changes taking place during LTP and LTD and show...
39.
Papoutsi A, Kastellakis G, Poirazi P
J Neurophysiol
. 2017 Jul;
118(4):1970-1983.
PMID: 28701532
While the morphology of basal dendritic trees in cortical pyramidal neurons varies, the functional implications of this diversity are just starting to emerge. In layer 5 pyramidal neurons of the...
40.
Mel B, Schiller J, Poirazi P
Curr Opin Neurobiol
. 2017 Apr;
43:177-186.
PMID: 28453975
The elaborate morphology, nonlinear membrane mechanisms and spatiotemporally varying synaptic activation patterns of dendrites complicate the expression, compartmentalization and modulation of synaptic plasticity. To grapple with this complexity, we start...