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Kyriaki Sidiropoulou

Explore the profile of Kyriaki Sidiropoulou including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 945
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Recent Articles
1.
Arbring Sjostrom T, Ivanov A, Kiani N, Bernacka-Wojcik I, Samuelsson J, Saarela Unemo H, et al.
Small . 2025 Mar; :e2410906. PMID: 40059561
The composition of the extracellular milieu can vary significantly under physiological and pathological conditions, thereby altering the functional set point of brain cells. While global changes in the extracellular milieu...
2.
Kokkali M, Karali K, Thanou E, Papadopoulou M, Zota I, Tsimpolis A, et al.
Mol Psychiatry . 2024 Nov; PMID: 39587294
Alzheimer's Disease (AD) is an incurable and debilitating progressive, neurodegenerative disorder which is the leading cause of dementia worldwide. Neuropathologically, AD is characterized by the accumulation of Aβ amyloid plaques...
3.
Plaitakis A, Sidiropoulou K, Kotzamani D, Litso I, Zaganas I, Spanaki C
Int J Mol Sci . 2024 May; 25(10). PMID: 38791334
Human evolution is characterized by rapid brain enlargement and the emergence of unique cognitive abilities. Besides its distinctive cytoarchitectural organization and extensive inter-neuronal connectivity, the human brain is also defined...
4.
Spanaki C, Sidiropoulou K, Petraki Z, Diskos K, Konstantoudaki X, Volitaki E, et al.
iScience . 2024 Feb; 27(2):108821. PMID: 38333701
The human brain is characterized by the upregulation of synaptic, mainly glutamatergic, transmission, but its evolutionary origin(s) remain elusive. Here we approached this fundamental question by studying mice transgenic (Tg)...
5.
Thomaidi M, Vagiaki L, Tripolitsiotis N, Angeli G, Zarganes-Tzitzikas T, Sidiropoulou K, et al.
ChemMedChem . 2022 Jun; 17(15):e202200246. PMID: 35642621
Local anesthetics occupy a prime position in clinical medicine as they temporarily relieve the pain by blocking voltage-gated sodium channels. However, limited structural diversity, problems with the efficiency of syntheses...
6.
Rogdakis T, Charou D, Latorrata A, Papadimitriou E, Tsengenes A, Athanasiou C, et al.
Biomedicines . 2022 Mar; 10(3). PMID: 35327415
Neurotrophins are growth factors that exert important neuroprotective effects by preventing neuronal death and synaptic loss. Nerve Growth Factor (NGF) acts through the activation of its high-affinity, pro-survival TrkA and...
7.
Kallergi E, Daskalaki A, Kolaxi A, Camus C, Ioannou E, Mercaldo V, et al.
Nat Commun . 2022 Feb; 13(1):680. PMID: 35115539
The pruning of dendritic spines during development requires autophagy. This process is facilitated by long-term depression (LTD)-like mechanisms, which has led to speculation that LTD, a fundamental form of synaptic...
8.
Kalemaki K, Velli A, Christodoulou O, Denaxa M, Karagogeos D, Sidiropoulou K
Cereb Cortex . 2021 Dec; 32(17):3633-3650. PMID: 34905772
The prefrontal cortex (PFC) is characterized by protracted maturation. The cellular mechanisms controlling the early development of prefrontal circuits are still largely unknown. Our study delineates the developmental cellular processes...
9.
Giakoumaki S, Sidiropoulou K, Stamatakis A
Front Behav Neurosci . 2021 Aug; 15:724509. PMID: 34335200
No abstract available.
10.
Plataki M, Diskos K, Sougklakos C, Velissariou M, Georgilis A, Stavroulaki V, et al.
Front Behav Neurosci . 2021 Jun; 15:689193. PMID: 34177484
The neonatal MK-801 model of schizophrenia has been developed based on the neurodevelopmental and NMDA receptor hypofunction hypotheses of schizophrenia. This animal model is generated with the use of the...