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Nestoras Karathanasis

Explore the profile of Nestoras Karathanasis including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 164
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Recent Articles
1.
Karathanasis N, Spyrou G
Cancers (Basel) . 2025 Jan; 17(2). PMID: 39858113
Background: The accurate staging of multiple myeloma (MM) is essential for optimizing treatment strategies, while predicting the progression of asymptomatic patients, also referred to as monoclonal gammopathy of undetermined significance...
2.
Karathanasis N, Papasavva P, Oulas A, Spyrou G
Comput Methods Programs Biomed . 2024 Sep; 257:108432. PMID: 39316958
Background And Objective: The standard of care in Acute Myeloid Leukemia patients has remained essentially unchanged for nearly 40 years. Due to the complicated mutational patterns within and between individual...
3.
Oulas A, Savva K, Karathanasis N, Spyrou G
PLoS Comput Biol . 2024 Apr; 20(4):e1011550. PMID: 38635836
Prioritization or ranking of different cell types in a single-cell RNA sequencing (scRNA-seq) framework can be performed in a variety of ways, some of these include: i) obtaining an indication...
4.
Neves A, Cuesta I, Hjerde E, Klemetsen T, Salgado D, van Helden J, et al.
Front Public Health . 2023 Dec; 11:1289945. PMID: 38074768
The COVID-19 pandemic has exemplified the importance of interoperable and equitable data sharing for global surveillance and to support research. While many challenges could be overcome, at least in some...
5.
Karathanasis N, Hwang D, Heng V, Abhimannyu R, Slogoff-Sevilla P, Buchel G, et al.
PLoS Comput Biol . 2022 Nov; 18(11):e1010615. PMID: 36355750
The "replication crisis" is a methodological problem in which many scientific research findings have been difficult or impossible to replicate. Because the reproducibility of empirical results is an essential aspect...
6.
Planell N, Lagani V, Sebastian-Leon P, van der Kloet F, Ewing E, Karathanasis N, et al.
Front Genet . 2021 Mar; 12:620453. PMID: 33747045
Technologies for profiling samples using different omics platforms have been at the forefront since the human genome project. Large-scale multi-omics data hold the promise of deciphering different regulatory layers. Yet,...
7.
Loher P, Karathanasis N
Front Genet . 2021 Feb; 11:612840. PMID: 33633771
The development of single-cell sequencing technologies has allowed researchers to gain important new knowledge about the expression profile of genes in thousands of individual cells of a model organism or...
8.
Loher P, Karathanasis N, Londin E, Bray P, Pliatsika V, Telonis A, et al.
Bioinformatics . 2021 Jan; 37(13):1828-1838. PMID: 33471076
Motivation: MicroRNA (miRNA) precursor arms give rise to multiple isoforms simultaneously called 'isomiRs.' IsomiRs from the same arm typically differ by a few nucleotides at either their 5' or 3'...
9.
Tanevski J, Nguyen T, Truong B, Karaiskos N, Ahsen M, Zhang X, et al.
Life Sci Alliance . 2020 Sep; 3(11). PMID: 32972997
Single-cell RNA-sequencing (scRNAseq) technologies are rapidly evolving. Although very informative, in standard scRNAseq experiments, the spatial organization of the cells in the tissue of origin is lost. Conversely, spatial RNA-seq...
10.
Fernandes S, Morikawa H, Ewing E, Ruhrmann S, Joshi R, Lagani V, et al.
Sci Rep . 2019 Aug; 9(1):11996. PMID: 31427643
Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system with prominent neurodegenerative components. The triggering and progression of MS is associated with transcriptional and epigenetic alterations in...