P T van der Saag
Overview
Explore the profile of P T van der Saag including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
3069
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Recent Articles
1.
Windahl S, Lagerquist M, Andersson N, Jochems C, Kallkopf A, Hakansson C, et al.
Endocrinology
. 2007 Sep;
148(12):5688-95.
PMID: 17761761
Estrogen has bone protective effects, but the exact mechanism behind these effects remains unclear. The aim of the present study was to identify the primary target cells in bone for...
2.
Lemmen J, Arends R, van Boxtel A, van der Saag P, van der Burg B
J Mol Endocrinol
. 2004 Jun;
32(3):689-701.
PMID: 15171709
With the aim of developing an in vivo model that directly detects activation of estrogen receptors (ERs), transgenic mice carrying a luciferase reporter gene were generated. The luciferase reporter gene...
3.
Vermeer H, Hendriks-Stegeman B, van den Brink C, van der Saag P, van der Burg B, van Buul-Offers S, et al.
Clin Endocrinol (Oxf)
. 2003 Jun;
59(1):49-55.
PMID: 12807503
Objective: Some patients develop side-effects even on relatively low doses of topically administered glucocorticoids (GCs), while others appear to be less sensitive to GCs. We have developed and validated a...
4.
Lemmen J, van den Brink C, Legler J, van der Saag P, van der Burg B
J Endocrinol
. 2002 Sep;
174(3):435-46.
PMID: 12208664
Numerous steroid hormones are present in the foetus but their potential to activate oestrogen receptor (ER) alpha and/or beta is largely unknown. In this study, in vitro assays were developed...
5.
Wissink S, van der Burg B, Katzenellenbogen B, van der Saag P
Mol Endocrinol
. 2001 Mar;
15(4):543-52.
PMID: 11266506
Estrogen exerts profound effects on mood and mental state. The ability of estrogen to modulate serotonergic function raises the possibility that it may play a role in the mechanism associated...
6.
Quaedackers M, van den Brink C, Wissink S, Schreurs R, Gustafsson J, van der Saag P, et al.
Endocrinology
. 2001 Feb;
142(3):1156-66.
PMID: 11181531
Estrogens are important mediators of bone homeostasis, and postmenopausal estrogen replacement therapy is extensively used to prevent osteoporosis. The biological effects of estrogen are mediated by receptors belonging to the...
7.
Zomer A, van der Burg B, Jansen G, Wanders R, Poll-The B, van der Saag P
J Lipid Res
. 2000 Nov;
41(11):1801-7.
PMID: 11060349
Phytanic acid and pristanic acid are branched-chain fatty acids, present at micromolar concentrations in the plasma of healthy individuals. Here we show that both phytanic acid and pristanic acid activate...
8.
KESTER H, Goumans M, van Rooijen M, van der Saag P, van der Burg B, Mummery C
Dev Dyn
. 2000 Jul;
218(4):563-72.
PMID: 10906776
TSC-22 is a highly conserved member of a novel family of transcription factors, that is a direct target of transforming growth factor-beta (TGF-beta) in osteoblastic cells. We have investigated the...
9.
Zomer A, Jansen G, van der Burg B, Verhoeven N, Jakobs C, van der Saag P, et al.
Eur J Biochem
. 2000 Jun;
267(13):4063-7.
PMID: 10866807
Phytanic acid (3,7,11,15-tetramethylhexadecanoic acid) is a branched-chain fatty acid present in various dietary products such as milk, cheese and fish. In patients with Refsum disease, accumulation of phytanic acid occurs...
10.
van der Burg B, Sonneveld E, Lemmen J, van der Saag P
Int J Dev Biol
. 2000 Feb;
43(7):735-43.
PMID: 10668982
Retinoids and estrogens are small lipophilic compounds fulfilling important biological roles in vertebrate development, reproduction and homeostasis. Both types of ligands are regulators of gene transcription by binding to (nuclear)...