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B M van der Leede

Explore the profile of B M van der Leede including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 134
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Recent Articles
1.
Lovell D, Fellows M, Saul J, Whitwell J, Custer L, Dertinger S, et al.
Mutat Res Genet Toxicol Environ Mutagen . 2020 Feb; 849:503086. PMID: 32087845
A database of micronuclei counts for historical negative control data from rat in vivo micronuclei tests performed in 10 different laboratories was established. Data were available from over 4000 negative...
2.
Sonneveld E, van den Brink C, van der Leede B, Schulkes R, Petkovich M, van der Burg B, et al.
Cell Growth Differ . 1998 Aug; 9(8):629-37. PMID: 9716180
We report on the isolation of a cytochrome P450 (CYP)-like retinoic acid (RA) 4-hydroxylase cDNA from T-47D human breast cancer cells that is identical to the recently cloned hCYP26, which...
3.
van der Leede B, van den Brink C, Pijnappel W, Sonneveld E, van der Saag P, van der Burg B
J Biol Chem . 1997 Jul; 272(29):17921-8. PMID: 9218416
Previous studies have shown that all-trans-retinoic acid (RA) inhibits in vitro proliferation of hormone-dependent human breast cancer cells but not the growth of hormone-independent cells. Here we report on RA...
4.
KESTER H, van der Leede B, van der Saag P, van der Burg B
J Biol Chem . 1997 Jun; 272(26):16637-43. PMID: 9195978
Progesterone is an important regulator of normal and malignant breast epithelial cells. In addition to stimulating development of normal mammary epithelium, it can be used to treat hormone-dependent breast tumors....
5.
van der Leede B, Vroom T
Ned Tijdschr Geneeskd . 1997 Jun; 141(24):1183-8. PMID: 9380152
Retinoids are a group of natural and synthetic analogues of vitamin A (retinol). The biological activity of retinoids is mediated by multiple nuclear receptors which bind to specific DNA sequences...
6.
Westin S, Sonneveld E, van der Leede B, van der Saag P, Gustafsson J, Mode A
Mol Cell Endocrinol . 1997 May; 129(2):169-79. PMID: 9202400
Rats deficient in vitamin A express low levels of P4502C7 mRNA in the liver. Administration of all-trans retinoic acid (at-RA) or growth hormone (GH) to deficient animals only partially restored...
7.
Braakhuis B, Klaassen I, van der Leede B, Cloos J, Brakenhoff R, Copper M, et al.
Br J Cancer . 1997 Jan; 76(2):189-97. PMID: 9231918
Retinoids can reverse potentially premalignant lesions and prevent second primary tumours in patients with head and neck squamous cell carcinoma (HNSCC). Furthermore, it has been reported that acquired resistance to...
8.
van der Leede B, Geertzema J, Vroom T, Decimo D, Lutz Y, van der Saag P, et al.
Am J Pathol . 1996 Jun; 148(6):1905-14. PMID: 8669476
Retinoids are known to prevent mammary carcinogenesis in rodents and inhibit the growth of human breast cancer cells in vitro. Previously we demonstrated that retinoid inhibition of proliferation of human...
9.
van der Burg B, van der Leede B, de Laat S, van der Saag P
Mol Cell Endocrinol . 1995 Aug; 112(2):143-52. PMID: 7489817
We have studied the role of the AP1 transcription factor in the progression of human breast carcinomas. This progression is characterized by a loss of dependence for proliferation on mitogenic...
10.
van der Burg B, van der Leede B, Salverda S, de Laat S, van der Saag P
Mol Cell Endocrinol . 1993 Feb; 91(1-2):149-57. PMID: 8386111
Retinoic acid (RA) strongly inhibits proliferation of the estrogen (E2)-dependent human breast cancer cell lines MCF7, T47D, and ZR75-1, but not the E2-independent and E2 receptor (ER)-negative lines MDA-MB231, MDA-MB468,...