P Ferrier
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Explore the profile of P Ferrier including associated specialties, affiliations and a list of published articles.
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67
Citations
1202
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Recent Articles
1.
Ribas R, Oback B, Ritchie W, Chebotareva T, Ferrier P, Clarke C, et al.
Cloning Stem Cells
. 2005 Jun;
7(2):126-38.
PMID: 15971986
In the present study, a zona-free nuclear transfer (NT) technique, which had been originally developed in cattle, was modified for the mouse. Steps involved in this approach include removing the...
2.
Mancini S, Candeias S, Di Santo J, Ferrier P, Marche P, Jouvin-Marche E
J Immunol
. 2001 Oct;
167(8):4485-93.
PMID: 11591775
During thymocyte differentiation, TCRA genes are massively rearranged only after productively rearranged TCRB genes are expressed in association with pTalpha and CD3 complex molecules within a pre-TCR. Signaling from the...
3.
Yeh J, Lecine P, Nunes J, Spicuglia S, Ferrier P, Olive D, et al.
Mol Cell Biol
. 2001 Jun;
21(14):4515-27.
PMID: 11416131
The interaction of interleukin-2 (IL-2) with its receptor (IL-2R) critically regulates the T-cell immune response, and the alpha chain CD25/IL-2Ralpha is required for the formation of the high-affinity receptor. Tissue-specific,...
4.
Nal B, Mohr E, Ferrier P
Bioessays
. 2001 Jun;
23(6):473-6.
PMID: 11385626
In this post-sequencing era, geneticists can focus on functional genomics on a much larger scale than ever before. One goal is the discovery and elucidation of the intricate genetic networks...
5.
Leduc I, Karsunky H, Mathieu N, Schmidt T, Verthuy C, Ferrier P, et al.
Int Immunol
. 2000 Sep;
12(10):1389-96.
PMID: 11007756
We demonstrate that overexpression of Pim-1, a cytoplasmic serine/threonine kinase of poorly defined function, results in the development of substantial numbers of CD4(+)CD8(+) double-positive thymocytes in two independent knock-out mouse...
6.
Mathieu N, Hempel W, Spicuglia S, Verthuy C, Ferrier P
J Exp Med
. 2000 Sep;
192(5):625-36.
PMID: 10974029
Gene targeting studies have shown that T cell receptor (TCR)-beta gene expression and recombination are inhibited after deletion of an enhancer (Ebeta) located at the 3' end of the approximately...
7.
Leduc I, Hempel W, Mathieu N, Verthuy C, Bouvier G, Watrin F, et al.
J Immunol
. 2000 Jul;
165(3):1364-73.
PMID: 10903739
T cell differentiation in the mouse thymus is an intricate, highly coordinated process that requires the assembly of TCR complexes from individual components, including those produced by the precisely timed...
8.
Spicuglia S, Payet D, Tripathi R, Rameil P, Verthuy C, Imbert J, et al.
EMBO J
. 2000 May;
19(9):2034-45.
PMID: 10790370
The TCR alpha enhancer (Ealpha) has served as a paradigm for studying how enhancers organize trans-activators into nucleo-protein complexes thought to recruit and synergistically stimulate the transcriptional machinery. Little is...
9.
Carrier A, Nguyen C, Victorero G, Granjeaud S, Rocha D, Bernard K, et al.
Immunogenetics
. 2000 Jan;
50(5-6):255-70.
PMID: 10630289
A set of 3000 mouse thymus cDNAs was analyzed by extensive measurement of expression using complex-probe hybridization of DNA arrays ("quantitative differential screening"). The complex probes were initially prepared using...
10.
Definition of a T-cell receptor beta gene core enhancer of V(D)J recombination by transgenic mapping
Tripathi R, Mathieu N, Spicuglia S, Payet D, Verthuy C, Bouvier G, et al.
Mol Cell Biol
. 1999 Dec;
20(1):42-53.
PMID: 10594007
V(D)J recombination in differentiating lymphocytes is a highly regulated process in terms of both cell lineage and the stage of cell development. Transgenic and knockout mouse studies have demonstrated that...