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C Verthuy

Explore the profile of C Verthuy including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 164
Followers 0
Related Specialties
Allergy & Immunology
Science
General Medicine
Top 10 Co-Authors
P Ferrier
W M Hempel
N Mathieu
G Bouvier
S Spicuglia
F Watrin
R K Tripathi
D Payet
I Leduc
P Naquet
Published In
Proc Natl Acad Sci U S A
J Immunol
Mol Cell Biol
J Exp Med
EMBO J
Affiliations
Soon will be listed here.
Recent Articles
1.
The Pim-1 kinase stimulates maturation of TCRbeta-deficient T cell progenitors: implications for the mechanism of Pim-1 action
Leduc I, Karsunky H, Mathieu N, Schmidt T, Verthuy C, Ferrier P, et al.
Int Immunol . 2000 Sep; 12(10):1389-96. PMID: 11007756
We demonstrate that overexpression of Pim-1, a cytoplasmic serine/threonine kinase of poorly defined function, results in the development of substantial numbers of CD4(+)CD8(+) double-positive thymocytes in two independent knock-out mouse...
2.
Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination
Mathieu N, Hempel W, Spicuglia S, Verthuy C, Ferrier P
J Exp Med . 2000 Sep; 192(5):625-36. PMID: 10974029
Gene targeting studies have shown that T cell receptor (TCR)-beta gene expression and recombination are inhibited after deletion of an enhancer (Ebeta) located at the 3' end of the approximately...
3.
T cell development in TCR beta enhancer-deleted mice: implications for alpha beta T cell lineage commitment and differentiation
Leduc I, Hempel W, Mathieu N, Verthuy C, Bouvier G, Watrin F, et al.
J Immunol . 2000 Jul; 165(3):1364-73. PMID: 10903739
T cell differentiation in the mouse thymus is an intricate, highly coordinated process that requires the assembly of TCR complexes from individual components, including those produced by the precisely timed...
4.
TCRalpha enhancer activation occurs via a conformational change of a pre-assembled nucleo-protein complex
Spicuglia S, Payet D, Tripathi R, Rameil P, Verthuy C, Imbert J, et al.
EMBO J . 2000 May; 19(9):2034-45. PMID: 10790370
The TCR alpha enhancer (Ealpha) has served as a paradigm for studying how enhancers organize trans-activators into nucleo-protein complexes thought to recruit and synergistically stimulate the transcriptional machinery. Little is...
5.
Definition of a T-cell receptor beta gene core enhancer of V(D)J recombination by transgenic mapping
Tripathi R, Mathieu N, Spicuglia S, Payet D, Verthuy C, Bouvier G, et al.
Mol Cell Biol . 1999 Dec; 20(1):42-53. PMID: 10594007
V(D)J recombination in differentiating lymphocytes is a highly regulated process in terms of both cell lineage and the stage of cell development. Transgenic and knockout mouse studies have demonstrated that...
6.
Natural killer cell acceptance of H-2 mismatch bone marrow grafts in transgenic mice expressing HLA-Cw3 specific killer cell inhibitory receptor
CAMBIAGGI A, Verthuy C, Naquet P, Romagne F, Ferrier P, Biassoni R, et al.
Proc Natl Acad Sci U S A . 1997 Jul; 94(15):8088-92. PMID: 9223319
Natural killer (NK) cells express killer cell inhibitory receptors (KIRs) for major histocompatibility complex class I molecules. Engagement of these surface receptors inhibits NK cell cytotoxic programs. KIR can also...
7.
Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development
Bouvier G, Watrin F, Naspetti M, Verthuy C, Naquet P, Ferrier P
Proc Natl Acad Sci U S A . 1996 Jul; 93(15):7877-81. PMID: 8755570
Intrathymic T-cell development requires temporally regulated rearrangement and expression of T-cell receptor (TCR) genes. To assess the role of the TCR beta gene transcriptional enhancer (Ebeta) in this process, mouse...