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L R Covey

Explore the profile of L R Covey including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 377
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Recent Articles
1.
Moore C, Liu Y, Shao C, Covey L, Morse 3rd H, Xie P
Leukemia . 2011 Oct; 26(5):1122-7. PMID: 22033491
No abstract available.
2.
Bhushan A, Covey L
Immunol Res . 2002 Jan; 24(3):311-24. PMID: 11817328
Hyper-IgM (HIM) syndrome is a rare immunodeficiency characterized by low or absent IgG, IgA, and IgE with normal or elevated levels of IgM. This disorder can be acquired or familial...
3.
Bhushan A, Covey L
Eur J Immunol . 2001 Feb; 31(2):653-64. PMID: 11180131
To understand the underlying basis for the strong IL-4- and CD154-mediated Igamma1 promoter activity in Ramos 2G6 B cells, we carried out transient transfection assays with luciferase-based constructs containing approximately...
4.
Barnhart B, Kosinski P, Wang Z, Ford G, Kiledjian M, Covey L
J Immunol . 2000 Oct; 165(8):4478-86. PMID: 11035087
CD154 expression is regulated throughout a time course of CD3-dependent T cell activation by differential mRNA decay. To understand the molecular basis of the "stability" phase of this pathway, experiments...
5.
Bhushan A, Barnhart B, Shone S, Song C, Covey L
J Immunol . 2000 Mar; 164(6):2871-80. PMID: 10706672
To establish the underlying cause of hyper-IgM syndrome in one female patient, B cell function was examined in response to CD40- and IL-4-mediated pathways. When CD40-induced functional responses were measured...
6.
Barnhart B, Ford G, Bhushan A, Song C, Covey L
Immunology . 2000 Jan; 99(1):54-61. PMID: 10651941
We report the characterization of a naturally occurring polymorphism in CD40 ligand (CD40L, CD154) expressed by activated T cells from a young female patient. This polymorphism encodes a nonconservative Gly...
7.
Ford G, Barnhart B, Shone S, Covey L
J Immunol . 1999 Apr; 162(7):4037-44. PMID: 10201926
The CD154 protein (CD40 ligand), which is critical to the regulation of both humoral and cellular immune responses, is expressed transiently on the surface of activated CD4+ T cells. To...
8.
Ford G, Yin C, Barnhart B, Sztam K, Covey L
J Immunol . 1998 Apr; 160(2):595-605. PMID: 9551893
The CD40:CD40 ligand (CD40L) interaction plays a critical role in T cell-dependent isotype switching. To elucidate the role of CD40 signaling in the activation of gamma germline transcription and as...
9.
Yellin M, Sinning J, Covey L, Sherman W, Lee J, Sippel K, et al.
J Immunol . 1994 Jul; 153(2):666-74. PMID: 7517421
Activation-induced cell surface molecules are involved in mediating bidirectional T-B lymphocyte signaling that is important in the induction of T or B lymphocyte effector functions. In this regard, T-BAM/CD40-L is...
10.
Covey L, Cleary A, Yellin M, Ware R, Sullivan G, BELKO J, et al.
Mol Immunol . 1994 Apr; 31(6):471-84. PMID: 7514269
"T-cell B-cell Activating Molecule" (T-BAM) is an activation-induced surface protein on CD4+ T cells that mediates a contact-dependent signal for B cell differentiation and immunoglobulin (Ig) secretion. The T-BAM protein...