P C Simpson
Overview
Explore the profile of P C Simpson including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
48
Citations
1024
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Rupert C, Lopez J, Cortez-Toledo E, De la Cruz Cabrera O, Chesler N, Simpson P, et al.
Am J Physiol Heart Circ Physiol
. 2023 Jan;
324(3):H293-H304.
PMID: 36637971
Chronic stimulation of cardiac α-adrenergic receptors (α-ARs) improves symptoms in multiple preclinical models of heart failure. However, the translational significance remains unclear. Human engineered heart tissues (EHTs) provide a means...
2.
Methven L, Simpson P, McGrath J
Br J Pharmacol
. 2009 Nov;
158(7):1663-75.
PMID: 19888965
Background And Purpose: Theoretically, three alpha(1)-adrenoceptor subtypes can interact at the signalling level to alter vascular contraction or at the molecular level to alter each other's cellular location. The alpha(1A/B)-adrenoceptor...
3.
Muramatsu I, Morishima S, Suzuki F, Yoshiki H, Anisuzzaman A, Tanaka T, et al.
Br J Pharmacol
. 2008 Sep;
155(8):1224-34.
PMID: 18806813
Background And Purpose: The alpha(1L)-adrenoceptor has pharmacological properties that distinguish it from three classical alpha(1)-adrenoceptors (alpha(1A), alpha(1B) and alpha(1D)). The purpose of this was to identify alpha(1L)-adrenoceptors in mice and...
4.
Turcato S, Turnbull L, Wang G, Honbo N, Simpson P, Karliner J, et al.
Basic Res Cardiol
. 2006 Feb;
101(3):235-43.
PMID: 16450074
Unlabelled: The goal of this study was to determine if an ischemic preconditioning (IPC) protocol improved post-ischemic functional recovery of female mouse hearts. A previous study found that IPC did...
5.
Kinugawa K, Yonekura K, Ribeiro R, Eto Y, Aoyagi T, Baxter J, et al.
Circ Res
. 2001 Sep;
89(7):591-8.
PMID: 11577024
Physiological and pathological cardiac hypertrophy have directionally opposite changes in transcription of thyroid hormone (TH)-responsive genes, including alpha- and beta-myosin heavy chain (MyHC) and sarcoplasmic reticulum Ca(2+)-ATPase (SERCA), and TH...
6.
Nakamura A, Rokosh D, Paccanaro M, Yee R, Simpson P, Grossman W, et al.
Am J Physiol Heart Circ Physiol
. 2001 Aug;
281(3):H1104-12.
PMID: 11514276
Transverse aortic constriction (TAC) is an effective technique for inducing left ventricular (LV) hypertrophy in mice. With the use of transthoracic echocardiography and Doppler measurements, we studied the effects of...
7.
OConnell T, Rokosh D, Simpson P
Mol Pharmacol
. 2001 Apr;
59(5):1225-34.
PMID: 11306707
alpha1-Adrenergic receptor (AR) subtypes in the heart are expressed by myocytes but not by fibroblasts, a feature that distinguishes alpha1-ARs from beta-ARs. Here we studied myocyte-specific expression of alpha1-ARs, focusing...
8.
Baker A, Redfern C, Harwood M, Simpson P, Conklin B
Am J Physiol Heart Circ Physiol
. 2001 Mar;
280(4):H1653-9.
PMID: 11247776
Although increased G(i) signaling has been associated with dilated cardiomyopathy in humans, its role is not clear. Our goal was to determine the effects of chronically increased G(i) signaling on...
9.
Zuzarte P, Farrance I, Simpson P, Wildeman A
Biochim Biophys Acta
. 2000 Dec;
1517(1):82-90.
PMID: 11118619
The large tumor antigen (TAg) of simian virus 40 is able to transform cells through interactions with cellular proteins, notably p53 and Rb. Among the other proteins that form complexes...
10.
Deng X, Rokosh D, Simpson P
Circ Res
. 2000 Oct;
87(9):781-8.
PMID: 11055982
Cultured neonatal rat cardiac myocytes have been used extensively to study cellular and molecular mechanisms of cardiac hypertrophy. However, there are only a few studies in cultured mouse myocytes despite...