R A Mathies
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Explore the profile of R A Mathies including associated specialties, affiliations and a list of published articles.
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119
Citations
2378
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Recent Articles
1.
New J, Mathies R, Price M, Cole M, Golozar M, Spathis V, et al.
Meteorit Planet Sci
. 2020 May;
55(3):465-479.
PMID: 32362737
The presence and accessibility of a sub-ice-surface saline ocean at Enceladus, together with geothermal activity and a rocky core, make it a compelling location to conduct further, in-depth, astrobiological investigations...
2.
Schnedermann C, Yang X, Liebel M, Spillane K, Lugtenburg J, Fernandez I, et al.
Nat Chem
. 2018 Mar;
10(4):449-455.
PMID: 29556051
Vibronic coupling is key to efficient energy flow in molecular systems and a critical component of most mechanisms invoking quantum effects in biological processes. Despite increasing evidence for coherent coupling...
3.
Du K, Cai H, Park M, Wall T, Stott M, Alfson K, et al.
Biosens Bioelectron
. 2017 Jan;
91:489-496.
PMID: 28073029
An automated microfluidic sample preparation multiplexer (SPM) has been developed and evaluated for Ebola virus detection. Metered air bubbles controlled by microvalves are used to improve bead-solution mixing thereby enhancing...
4.
Cai H, Parks J, Wall T, Stott M, Stambaugh A, Alfson K, et al.
Sci Rep
. 2015 Sep;
5:14494.
PMID: 26404403
The massive outbreak of highly lethal Ebola hemorrhagic fever in West Africa illustrates the urgent need for diagnostic instruments that can identify and quantify infections rapidly, accurately, and with low...
5.
Parks J, Olson M, Kim J, Ozcelik D, Cai H, Carrion Jr R, et al.
Biomicrofluidics
. 2015 Jan;
8(5):054111.
PMID: 25584111
We describe the integration of an actively controlled programmable microfluidic sample processor with on-chip optical fluorescence detection to create a single, hybrid sensor system. An array of lifting gate microvalves...
6.
Clark S, Mathies R
Anal Chem
. 2011 Jun;
69(7):1355-63.
PMID: 21639343
Methods have been developed for performing accurate, high-resolution, multiplex capillary electrophoresis separations of dsDNA using dimeric intercalation dyes as noncovalent labeling reagents. The quality of these separations is highly dependent...
7.
Kim J, McCamant D, Zhu L, Mathies R
J Phys Chem B
. 2006 Jun;
105(6):1240-9.
PMID: 16755302
Picosecond time-resolved resonance Raman spectroscopy is used to probe the structural changes of rhodopsin's retinal chromophore as the cis-to-trans isomerization reaction occurs that initiates vision. Room-temperature resonance Raman spectra of...
8.
Kamei T, Toriello N, Lagally E, Blazej R, Scherer J, Street R, et al.
Biomed Microdevices
. 2005 Jun;
7(2):147-52.
PMID: 15940430
We have developed an integrated hydrogenated amorphous silicon (a-Si:H) fluorescence detector for microfluidic genetic analysis. It consists of a half-ball lens, a ZnS/YF3 multilayer optical interference filter with a pinhole,...
9.
Lagally E, Scherer J, Blazej R, Toriello N, Diep B, Ramchandani M, et al.
Anal Chem
. 2004 May;
76(11):3162-70.
PMID: 15167797
An integrated portable genetic analysis microsystem including PCR amplification and capillary electrophoretic (CE) analysis coupled with a compact instrument for electrical control and laser-excited fluorescence detection has been developed. The...
10.
Lagally E, Emrich C, Mathies R
Lab Chip
. 2004 Apr;
1(2):102-7.
PMID: 15100868
A fully integrated genomic analysis microsystem including microfabricated heaters, temperature sensors, and PCR chambers directly connected to capillary electrophoretic separation channels has been constructed. Valves and hydrophobic vents provide controlled...